2,3,4-Trifluorobenzyl bromide (CAS 157911-55-2)
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2,3,4-Trifluorobenzyl bromide is a halogenated organic compound that is widely used in the field of organic chemistry for various synthetic applications. Its primary role is as a benzylating agent, where it introduces the trifluoromethylated benzyl group into other molecules, aiding in the study of the influence of trifluoromethyl groups on molecular properties like stability and reactivity. This compound is particularly valuable in the synthesis of complex fluorinated molecules, which are of interest due to their unique physical and chemical characteristics. Researchers also utilize this reagent in the functionalization of aromatic compounds, employing it in palladium-catalyzed cross-coupling reactions, a method that is foundational to the construction of many biologically active compounds and materials. Additionally, the presence of the bromide moiety makes it a suitable electrophile for various nucleophilic substitution reactions, a fundamental type of reaction explored in mechanistic organic chemistry.
2,3,4-Trifluorobenzyl bromide (CAS 157911-55-2) References
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- Asymmetric synthesis of α,β-epoxysulfones via phase-transfer catalytic Darzens reaction | Ku, J. M., Yoo, M. S., Park, H. G., Jew, S. S., & Jeong, B. S. 2007. Tetrahedron. 63(34): 8099-8103.
- Synthesis of (αR, βS)-epoxyketones by asymmetric epoxidation of chalcones with cinchona phase-transfer catalysts | Yoo, M. S., Kim, D. G., Ha, M. W., Jew, S. S., Park, H. G., & Jeong, B. S. 2010. Tetrahedron Letters. 51(42): 5601-5603.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2,3,4-Trifluorobenzyl bromide, 1 g | sc-225623 | 1 g | $96.00 |