2,3,4,6-Tetra-O-pivaloyl-β-D-galactopyranosyl isothiocyanate (CAS 147948-52-5)

2,3,4,6-Tetra-O-pivaloyl-β-D-galactopyranosyl isothiocyanate is a potent chemical reagent widely used in glycobiology research. This compound is a derivative of galactose, modified with pivaloyl groups to enhance its stability and reactivity. It serves as an effective glycosyl donor in glycosylation reactions, facilitating the synthesis of glycosidic linkages. The isothiocyanate moiety allows for the introduction of thiocyanate groups into biomolecules, enabling the study of carbohydrate-protein interactions and the formation of glycoproteins. Research has demonstrated its utility in the synthesis of oligosaccharides and glycoconjugates, crucial for understanding cell surface recognition processes. Additionally, it plays a role in the modification of natural products and the development of carbohydrate-based probes for molecular imaging and diagnostics. Studies have also explored its application in the design of glycomimetics, molecules that mimic the structure of carbohydrates to investigate biological functions and mechanisms. This chemical′s ability to facilitate the precise attachment of carbohydrate moieties to various substrates makes it invaluable for probing the structural and functional roles of carbohydrates in biological systems. Researchers leverage its reactivity and specificity to explain complex carbohydrate structures and their implications in cellular signaling and molecular recognition processes.