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2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl isothiocyanate (CAS 14152-97-7)

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Alternate Names:
GITC
Application:
2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl isothiocyanate is 2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl isothiocyanate is a chiral reagent used for resolution of amino acid derivatives.
CAS Number:
14152-97-7
Molecular Weight:
389.38
Molecular Formula:
C15H19NO9S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl isothiocyanate (TATG) is a versatile compound derived from glucose, its broad utility in diverse scientific applications. Its applications span cell culture and gene expression analysis. In cell culture, 2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl isothiocyanate (TATG) has shed light on the influence of glucose on cell viability and metabolism. Gene expression studies have harnessed 2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl isothiocyanate to explore how glucose impacts gene expression levels. While the complete mechanism of action of 2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl isothiocyanate remains elusive, current understanding suggests that it engages specific receptors on the cell surface, initiating a series of biochemical reactions that contribute to the desired outcomes.


2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl isothiocyanate (CAS 14152-97-7) References

  1. Reversed-phase high performance liquid chromatographic separation of the enantiomers of terbutaline by derivatization with 2,3,4,6-tetra-o-acetyl-beta-D-glucopyranosyl isothiocyanate.  |  Kim, KH., et al. 2000. Arch Pharm Res. 23: 26-30. PMID: 10728652
  2. Reversed-phase high-performance liquid chromatographic analysis of atenolol enantiomers in rat hepatic microsome after chiral derivatizaton with 2,3,4,6,-tetra-O-acetyl-beta-D-glycopyranosyl isothiocyanate.  |  Li, X., et al. 2000. J Chromatogr B Biomed Sci Appl. 742: 433-9. PMID: 10901149
  3. Enantiomeric purity test of bevantolol by reversed-phase high performance liquid chromatography after derivatization with 2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl isothiocyanate.  |  Kim, KH., et al. 2000. Arch Pharm Res. 23: 568-73. PMID: 11156176
  4. Chiral separation of pheniramine-like 3-phenyl-3-heteroarylpropylamines by CE and HPLC methods.  |  Schuster, A., et al. 2001. Chirality. 13: 285-93. PMID: 11370017
  5. Determination of the enantiomers of fenoldopam in human plasma by reversed-phase high-performance liquid chromatography after chiral derivatization.  |  Boppana, VK., et al. 1992. J Chromatogr. 592: 317-22. PMID: 1349896
  6. Simultaneous determination of the enantiomers of esmolol and its acid metabolite in human plasma by reversed phase liquid chromatography with solid-phase extraction.  |  Tang, YH., et al. 2004. J Chromatogr B Analyt Technol Biomed Life Sci. 805: 249-54. PMID: 15135097
  7. Stereoselective RP-HPLC determination of esmolol enantiomers in human plasma after pre-column derivatization.  |  Tang, YH., et al. 2004. J Biochem Biophys Methods. 59: 159-66. PMID: 15163527
  8. Determination of enantiomeric impurity in besifloxacin hydrochloride by chiral high-performance liquid chromatography with precolumn derivatization.  |  Wang, Z., et al. 2012. Chirality. 24: 526-31. PMID: 22593028
  9. Sungsanpin, a lasso peptide from a deep-sea streptomycete.  |  Um, S., et al. 2013. J Nat Prod. 76: 873-9. PMID: 23662937
  10. Reversed-phase liquid chromatographic separation of enantiomeric and diastereomeric bases related to chloramphenicol and thiamphenicol.  |  Gal, J. and Meyer-Lehnert, S. 1988. J Pharm Sci. 77: 1062-5. PMID: 3244112
  11. Enantioselective determination of sotalol enantiomers in biological fluids using high-performance liquid chromatography.  |  Shimizu, T., et al. 1995. J Chromatogr B Biomed Appl. 674: 77-83. PMID: 8749254
  12. Distribution of metoprolol enantiomers in a fatal overdose.  |  Mozayani, A., et al. 1995. J Anal Toxicol. 19: 519-21. PMID: 8926749
  13. [Highly effective separation and highly sensitive detection for clinical chemistry and biochemistry].  |  Kinoshita, T. 1998. Yakugaku Zasshi. 118: 31-50. PMID: 9513578
  14. Resolution of salbutamol enantiomers in human urine by reversed-phase high performance liquid chromatography after derivatization with 2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl isothiocyanate.  |  Kim, KH. and Kim, TK. 1998. Arch Pharm Res. 21: 217-22. PMID: 9875434

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl isothiocyanate, 100 mg

sc-216269
100 mg
$184.00

2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl isothiocyanate, 1 g

sc-216269A
1 g
$921.00