2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl (1,3-Benzylidene)glycerol (CAS 213264-93-8)

2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl (1,3-Benzylidene)glycerol, commonly referred to as benzylidene glycerol, is a compound used in research for its role in carbohydrate chemistry and as a precursor for the synthesis of various glycoconjugates and glycosides. Its chemical structure, featuring a benzylidene group and multiple acetyl groups, lends itself to selective deprotection reactions, enabling the controlled synthesis of complex carbohydrates. Benzylidene glycerol serves as a key intermediate in the preparation of glycosyl donors and acceptors for glycosylation reactions, where it facilitates the formation of glycosidic bonds between carbohydrates and other biomolecules. Additionally, this compound is utilized in the synthesis of carbohydrate-based materials and bioactive molecules with tailored properties. Researchers exploit its versatile reactivity and compatibility with different protecting groups to design and construct structurally diverse carbohydrate derivatives for applications in glycobiology, chemical biology, and materials science. Ongoing investigations focus on developing novel synthetic methodologies and exploring the biological functions and applications of benzylidene glycerol-derived compounds in various research areas, including drug delivery, biomaterials, and carbohydrate-based tools and targets.