Date published: 2025-10-17

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2,3,4,5,6-Pentafluorotoluene (CAS 771-56-2)

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CAS Number:
771-56-2
Molecular Weight:
182.09
Molecular Formula:
C7H3F5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,3,4,5,6-Pentafluorotoluene, known as PFT, is a colorless and volatile liquid characterized by its sweet odor. This halogenated aromatic hydrocarbon finds versatile applications in organic synthesis, and analytical chemistry. Its fascinating properties include high reactivity, low toxicity, and limited solubility. In scientific research, 2,3,4,5,6-Pentafluorotoluene is widely used in organic synthesis to create various organic compounds, such as amides, ketones, and carboxylic acids. Furthermore, it can form complexes with various metals, such as iron and copper. The electron-withdrawing fluorine substituents on its aromatic ring contribute to 2,3,4,5,6-Pentafluorotoluene′s enhanced reactivity.


2,3,4,5,6-Pentafluorotoluene (CAS 771-56-2) References

  1. Gas-liquid chromatographic analysis of volatile short chain fatty acids in fecal samples as pentafluorobenzyl esters.  |  McGrath, LT., et al. 1992. Anal Biochem. 207: 227-30. PMID: 1481974
  2. Unusual collision-induced dissociation of fluorated and non-fluorated alpha-nitrotoluene analogs in a gas chromatograph triple-stage quadrupole mass spectrometer under electron-capturing negative-ion chemical ionization conditions.  |  Tsikas, D., et al. 2005. J Chromatogr A. 1067: 337-45. PMID: 15844540
  3. Nitric oxide detection methods in vitro and in vivo.  |  Goshi, E., et al. 2019. Med Gas Res. 9: 192-207. PMID: 31898604
  4. Catalytic Hydrodefluorination via Oxidative Addition, Ligand Metathesis, and Reductive Elimination at Bi(I)/Bi(III) Centers.  |  Pang, Y., et al. 2021. J Am Chem Soc. 143: 12487-12493. PMID: 34358426

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,3,4,5,6-Pentafluorotoluene, 10 g

sc-225631
10 g
$77.00