Date published: 2026-4-28

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2,3,4,5,6-Pentafluorobenzophenone (CAS 1536-23-8)

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Alternate Names:
(Pentafluorophenyl)(phenyl)methanone
CAS Number:
1536-23-8
Molecular Weight:
272.17
Molecular Formula:
C13H5F5O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,3,4,5,6-Pentafluorobenzophenone, referred to as PFB, is a synthetic organic compound characterized by its molecular formula, C13H4F5O. It presents as a colorless solid that readily dissolves in organic solvents and exhibits an exceptionally low vapor pressure. Owing to its distinctive properties, 2,3,4,5,6-Pentafluorobenzophenone has found widespread applications across various fields, including organic synthesis and materials science. Within the domain of organic synthesis, 2,3,4,5,6-Pentafluorobenzophenone serves as a valuable reagent, enabling the creation of diverse organic compounds like drugs, dyes, and polymers. Additionally, 2,3,4,5,6-Pentafluorobenzophenone plays a role in materials science, contributing to the synthesis of essential polymers like polyimides and polyurethanes. Although the precise mechanism of action for 2,3,4,5,6-Pentafluorobenzophenone remains incompletely understood, it is believed to function as an electron-deficient reagent, facilitating the formation of covalent bonds with electron-rich species. Moreover, 2,3,4,5,6-Pentafluorobenzophenone can act as an electrophile, engaging with nucleophiles to establish covalent bonds. This unique combination of characteristics makes 2,3,4,5,6-Pentafluorobenzophenone a versatile compound with significant importance in multiple scientific disciplines.


2,3,4,5,6-Pentafluorobenzophenone (CAS 1536-23-8) References

  1. Biological transformation, kinetics and dose-response assessments of bound musk ketone hemoglobin adducts in rainbow trout as biomarkers of environmental exposure.  |  Mottaleb, MA., et al. 2008. J Environ Sci (China). 20: 878-84. PMID: 18814586
  2. First regioselective cyclometalation reactions of cobalt in arylketones: C-H versus C-F activation.  |  Camadanli, S., et al. 2008. Dalton Trans. 5701-4. PMID: 18941655
  3. Relationship between odour-active compounds and flavour perception in meat from lambs fed different diets.  |  Resconi, VC., et al. 2010. Meat Sci. 85: 700-6. PMID: 20416794
  4. Color, lipid oxidation, sensory quality, and aroma compounds of beef steaks displayed under different levels of oxygen in a modified atmosphere package.  |  Resconi, VC., et al. 2012. J Food Sci. 77: S10-8. PMID: 22182210
  5. Highly fluorinated aryl-substituted tris(indazolyl)borate thallium complexes: diverse regiochemistry at the B-N bond.  |  Ojo, WS., et al. 2012. Inorg Chem. 51: 2893-901. PMID: 22339248
  6. Gas chromatographic-olfactometric aroma profile and quantitative analysis of volatile carbonyls of grilled beef from different finishing feed systems.  |  Resconi, VC., et al. 2012. J Food Sci. 77: S240-6. PMID: 22591324
  7. Functionalization of fluorinated molecules by transition-metal-mediated C-F bond activation to access fluorinated building blocks.  |  Ahrens, T., et al. 2015. Chem Rev. 115: 931-72. PMID: 25347593
  8. Efficient Access to Chiral Benzhydrols via Asymmetric Transfer Hydrogenation of Unsymmetrical Benzophenones with Bifunctional Oxo-Tethered Ruthenium Catalysts.  |  Touge, T., et al. 2016. J Am Chem Soc. 138: 10084-7. PMID: 27463264
  9. Magnetic field effects on the behavior of radicals in protein and DNA environments.  |  Mohtat, N., et al. 1998. Photochem Photobiol. 67: 111-8. PMID: 9477768

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,3,4,5,6-Pentafluorobenzophenone, 5 g

sc-260217
5 g
$91.00

2,3,4,5,6-Pentafluorobenzophenone, 25 g

sc-260217A
25 g
$234.00