Date published: 2025-11-30

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2,2′-Isopropylidenediphenol (CAS 7559-72-0)

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Alternate Names:
2,2′-(1-methylethylidene)bisphenol; 2,2′-isopropylidenediphenol; 2,2-Bis(2-hydroxyphenyl)propane; 2,2′-Dian; o,o′-Dian
CAS Number:
7559-72-0
Molecular Weight:
228.29
Molecular Formula:
C15H16O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,2′-Isopropylidenediphenol interacts with various cellular and molecular components through its ability to disrupt endocrine functions. 2,2′-Isopropylidenediphenol binds to estrogen receptors, mimicking estrogen and initiating similar biological responses within cells. Its interaction with these receptors can alter gene expression patterns, influencing processes related to growth, reproduction, and metabolic regulation. The compound′s estrogenic activity impacts the signaling pathways that regulate cellular proliferation and differentiation. It interferes with hormone synthesis and metabolism by competing with hormones for binding sites, disrupting the normal hormonal balance within organisms. This interference can lead to alterations in cell function and structure, particularly in hormone-sensitive tissues. The molecular architecture of 2,2′-Isopropylidenediphenol facilitates its integration into biological membranes, further influencing cellular communication and signaling mechanisms.


2,2′-Isopropylidenediphenol (CAS 7559-72-0) References

  1. Agonistic effects of diverse xenobiotics on the constitutive androstane receptor as detected in a recombinant yeast-cell assay.  |  Kamata, R., et al. 2018. Toxicol In Vitro. 46: 335-349. PMID: 28927721
  2. Functionalized polysulfones from 4,4-bis(4-hydroxyphenyl)pentanoic acid, 2,2-isopropylidenediphenol and bis(4-chlorophenyl) sulfone: synthesis, behaviour and polymer analogous amidation of the carboxylic groups  |  Koch T, Ritter H. 1994. Macromolecular Chemistry and Physics. 195: 1709-1717.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,2′-Isopropylidenediphenol, 100 mg

sc-489322
100 mg
$393.00