Molecular structure of 2,2′-Bicinchoninic Acid, CAS Number: 1245-13-2
2,2′-Bicinchoninic Acid (CAS 1245-13-2)
Alternate Names:
2,2′-Biquinoline-4,4′-dicarboxylic acid; bicinchoninic acid
Application:
2,2′-Bicinchoninic Acid is has been used in laboratories as a photometric reagent in protein assays
CAS Number:
1245-13-2
Molecular Weight:
344.32
Molecular Formula:
C20H12N2O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
2,2′-Bicinchoninic Acid is a compound that functions as a chelating agent in metal ion detection assays. It acts by forming stable complexes with transition metal ions such as copper(II) and nickel(II), which can be quantified spectrophotometrically. The mechanism of action involves the coordination of the bicinchoninic acid molecule with the metal ion, leading to the formation of a colored complex. This complex absorbs light at a specific wavelength, allowing for the measurement of metal ion concentration in solution. In research and development applications, 2,2′-Bicinchoninic Acid is utilized to determine the presence and concentration of metal ions in various samples.
2,2′-Bicinchoninic Acid (CAS 1245-13-2) References
- Rapid 2,2'-bicinchoninic-based xylanase assay compatible with high throughput screening. | Kenealy, WR. and Jeffries, TW. 2003. Biotechnol Lett. 25: 1619-23. PMID: 14584917
- Drug interference in the Bradford and 2,2'-bicinchoninic acid protein assays. | Marshall, T. and Williams, KM. 1991. Anal Biochem. 198: 352-4. PMID: 1724722
- Rapid determination of trace copper in animal feed based on micro-plate colorimetric reaction and statistical partitioning correction. | Niu, Y., et al. 2017. Food Chem. 221: 1406-1414. PMID: 27979108
- Assay of reducing sugars in the nanomole range with 2,2'-bicinchoninate. | Waffenschmidt, S. and Jaenicke, L. 1987. Anal Biochem. 165: 337-40. PMID: 3425902
- A Low-Volume, Parallel Copper-Bicinchoninic Acid (BCA) Assay for Glycoside Hydrolases. | Arnal, G., et al. 2023. Methods Mol Biol. 2657: 3-14. PMID: 37149519
- Measurement of protein in natural rubber latex. | Siler, DJ. and Cornish, K. 1995. Anal Biochem. 229: 278-81. PMID: 7485983
- A quantitative test for copper using bicinchoninic acid. | Brenner, AJ. and Harris, ED. 1995. Anal Biochem. 226: 80-4. PMID: 7785783
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2,2′-Bicinchoninic Acid, 1 g | sc-288354 | 1 g | $55.00 | |||
2,2′-Bicinchoninic Acid, 5 g | sc-288354A | 5 g | $159.00 |