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2-(2-Hydroxyphenyl)benzothiazole (CAS 3411-95-8)

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Alternate Names:
2-(2-Benzothiazolyl)phenol
CAS Number:
3411-95-8
Purity:
>99%
Molecular Weight:
227.28
Molecular Formula:
C13H9NOS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-(2-Hydroxyphenyl)benzothiazole (2-HPB) is a versatile phenolic compound featuring a thiazole ring, and its applications span across both scientific research and industrial production. Its multifaceted properties make it an excellent choice for various purposes. In scientific research, 2-(2-Hydroxyphenyl)benzothiazole finds widespread use as a reagent in organic synthesis, a catalyst for promoting organic reactions, and a fluorescent dye employed in fluorescence microscopy. Its importance doesn′t stop there, as it also serves as a building block in the synthesis of other compounds like 2-hydroxybenzothiazole and 2-hydroxybenzothiazole-3-sulfonate, further expanding its utility. When applied in organic synthesis, 2-(2-Hydroxyphenyl)benzothiazole acts as a catalyst, facilitating the transformation of substrates into desired products. In the realm of fluorescence microscopy, it takes on a different role as a fluorescent dye, emitting light upon exposure to ultraviolet light. Additionally, in the synthesis of various organic compounds, it acts as a reagent, playing a key role in converting substrates into the desired end products. 2-(2-Hydroxyphenyl)benzothiazole emerges as a remarkably versatile compound, unlocking various mechanisms of action, making it an indispensable tool in diverse scientific and industrial applications.


2-(2-Hydroxyphenyl)benzothiazole (CAS 3411-95-8) References

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  2. Ultrafast branching of reaction pathways in 2-(2'-hydroxyphenyl)benzothiazole in polar acetonitrile solution.  |  Mohammed, OF., et al. 2011. J Phys Chem A. 115: 7550-8. PMID: 21604716
  3. Photoinduced proton coupled electron transfer in 2-(2'-hydroxyphenyl)-benzothiazole.  |  Luber, S., et al. 2013. J Phys Chem A. 117: 5269-79. PMID: 23718689
  4. A single 2-(2'-hydroxyphenyl)benzothiazole derivative can achieve pure white-light emission.  |  Cheng, J., et al. 2014. Chem Asian J. 9: 3215-20. PMID: 25195657
  5. 2-(2-hydroxyphenyl)-benzothiazole (HBT)-rhodamine dyad: acid-switchable absorption and fluorescence of excited-state intramolecular proton transfer (ESIPT).  |  Majumdar, P. and Zhao, J. 2015. J Phys Chem B. 119: 2384-94. PMID: 25207667
  6. Excited-State Dynamics of 2-(2'-Hydroxyphenyl)benzothiazole: Ultrafast Proton Transfer and Internal Conversion.  |  Pijeau, S., et al. 2017. J Phys Chem A. 121: 4595-4605. PMID: 28558210
  7. Photochromism of 2-(2-Hydroxyphenyl) Benzothiazole (HBT) and Its Derivatives: A Theoretical Study.  |  Iravani, M. and Omidyan, R. 2018. J Phys Chem A. 122: 3182-3189. PMID: 29522339
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  9. Nitrostyrene-Modified 2-(2-Hydroxyphenyl)benzothiazole: Enol-Emission Solvatochromism by ESICT-ESIPT and Aggregation-Induced Emission Enhancement.  |  Niu, Y., et al. 2018. Chemistry. 24: 16670-16676. PMID: 30152561
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  11. Cooperation of ESIPT and ICT Processes in the Designed 2-(2'-Hydroxyphenyl)benzothiazole Derivative: A Near-Infrared Two-Photon Fluorescent Probe with a Large Stokes Shift for the Detection of Cysteine and Its Application in Biological Environments.  |  Long, Y., et al. 2020. Anal Chem. 92: 14236-14243. PMID: 33030891
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-(2-Hydroxyphenyl)benzothiazole, 5 g

sc-254038
5 g
$32.00