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[2-(2-(Fmoc-amino)ethoxy)ethoxy]acetic acid, used as a spacer in PNA synthesis, is an important compound in peptide chemistry. [2-(2-(Fmoc-amino)ethoxy)ethoxy]acetic acid is a PEG derivative with an Fmoc-protected amine and a carboxylic acid at the terminal position. The hydrophilic nature of the PEG spacer enhances solubility in aqueous environments. The Fmoc group can be deprotected under basic conditions to reveal the free amine, which can then be utilized for subsequent conjugations. Additionally, the terminal carboxylic acid can form a stable amide bond when reacted with primary amine groups in the presence of activators like EDC or DCC.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
{2-[2-(Fmoc-amino)ethoxy]ethoxy}acetic acid, 500 mg | sc-251686 | 500 mg | $175.00 |