Molecular structure of 2,2-Dimethoxypropane, CAS Number: 77-76-9
2,2-Dimethoxypropane (CAS 77-76-9)
Application:
2,2-Dimethoxypropane is a starting material and efficient tissue dehydration agent
CAS Number:
77-76-9
Purity:
≥98%
Molecular Weight:
104.15
Molecular Formula:
C5H12O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
2,2-Dimethoxypropane (DMP), with the chemical formula (CH3)2C(OCH3)2, is an organic compound that serves as a versatile reagent in synthetic organic chemistry. It is primarily used as an acetalization agent, which plays a key role in protecting carbonyl groups during chemical syntheses. DMP reacts with aldehydes and ketones to form acetals, a useful transformation that protects sensitive carbonyl groups from undesirable reactions during subsequent synthetic steps. The protective acetal groups can later be removed under acidic conditions, restoring the original carbonyl functionality. This makes DMP an invaluable tool in multi-step organic synthesis, allowing for the sequential construction of complex molecules without interference to the carbonyl group.
2,2-Dimethoxypropane (CAS 77-76-9) References
- Chemical dehydration of specimens with 2,2-dimethoxypropane (DMP) for paraffin processing of animal tissues: practical and economic advantages over dehydration in ethanol. | Conway, K. and Kiernan, JA. 1999. Biotech Histochem. 74: 20-6. PMID: 10190257
- Metastable ion study of organosilicon compounds. Part XIII: dimethoxydimethylsilane, (CH(3))(2)Si(OCH(3))(2), and dimethoxymethylsilane, CH(3)SiH(OCH(3))(2). | Tajima, S., et al. 2001. J Mass Spectrom. 36: 816-24. PMID: 11473405
- Oxo Ligand Reactivity in the [ReO(2)L(4)](+) Complex of 1-Methylimidazole. Preparation and Crystal Structures of Salts Containing the ReOL(4)(3+) Core and Apical CH(3)O(-), BF(3)O(2)(-), and (CH(3)O)(2)PO(2)(-) Groups. | Bélanger, S. and Beauchamp, AL. 1997. Inorg Chem. 36: 3640-3647. PMID: 11670055
- Preparation of serial sections of arthropods using 2,2-dimethoxypropane dehydration and epoxy resin embedding under vacuum. | Pernstich, A., et al. 2003. Biotech Histochem. 78: 5-9. PMID: 12713135
- Matrix isolation infrared and ab initio study of the conformations of 2,2-dimethoxypropane. | Venkatesan, V., et al. 2003. Spectrochim Acta A Mol Biomol Spectrosc. 59: 1497-507. PMID: 12714073
- Synthesis of bicyclo[5.3.0]azulene derivatives. | Nolting, DD., et al. 2009. Nat Protoc. 4: 1113-7. PMID: 19617883
- Determination of dimethyl sulfoxide and dimethyl sulfone in urine by gas chromatography-mass spectrometry after preparation using 2,2-dimethoxypropane. | Takeuchi, A., et al. 2010. Biomed Chromatogr. 24: 465-71. PMID: 19688817
- Synthetic mucin fragments. Benzyl O-beta-D-galactopyranosyl-(1----3)-O-(2-acetamido-2-deoxy-beta-D- glucopyranosyl)-(1----6)-2-acetamido-2-deoxy-alpha-D-galactopyranoside and O-alpha-L-fucopyranosyl-(1----3)-O-(2-acetamido-2-deoxy-beta-D- glucopyranosyl)-(1----6)-2-acetamido-2-deoxy-D-galactopyranose. | Thomas, RL., et al. 1989. Carbohydr Res. 189: 21-30. PMID: 2776135
- Direct methyl esterification with 2,2-dimethoxypropane for the simultaneous determination of urinary metabolites of toluene, xylene, styrene, and ethylbenzene by gas chromatography-mass spectrometry. | Takeuchi, A., et al. 2019. J Occup Health. 61: 82-90. PMID: 30698338
- Evaluation of a quick one-step sample preparation method for the determination of the isotopic fingerprint of rapeseed (Brassica napus): Investigation of the influence of the use of 2,2-dimethoxypropane on compound-specific stable carbon and hydrogen isotope analyses by gas chromatography combustion/pyrolysis isotope ratio mass spectrometry. | Xia, L., et al. 2021. Rapid Commun Mass Spectrom. 35: e9064. PMID: 33554384
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2,2-Dimethoxypropane, 500 ml | sc-209269 | 500 ml | $48.00 |