Date published: 2026-4-24

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2,2-Bis(4-hydroxyphenyl)butane (CAS 77-40-7)

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Alternate Names:
bisphenol B
CAS Number:
77-40-7
Purity:
≥97%
Molecular Weight:
242.32
Molecular Formula:
C16H18O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,2-Bis(4-hydroxyphenyl)butane serves as a subject of study in academic and research applications, particularly in the exploration of advanced polymer structures and their formation mechanisms. Researchers have investigated its behavior as a monomer in the polymerization process, examining how it contributes to the properties of experimental polycarbonates and resins on a molecular level. The focus in such studies is to understand the fundamental interactions that lead to enhanced thermal stability and structural integrity in synthesized polymers. Investigations into 2,2-Bis(4-hydroxyphenyl)butane also aim to map out its reactivity with various catalysts and under different conditions, which can lead to insights into new material design with potential applications that extend beyond current uses.


2,2-Bis(4-hydroxyphenyl)butane (CAS 77-40-7) References

  1. Determination of bisphenol a and bisphenol B residues in canned peeled tomatoes by reversed-phase liquid chromatography.  |  Grumetto, L., et al. 2008. J Agric Food Chem. 56: 10633-7. PMID: 18959420
  2. Bisphenol AF and Bisphenol B Exert Higher Estrogenic Effects than Bisphenol A via G Protein-Coupled Estrogen Receptor Pathway.  |  Cao, LY., et al. 2017. Environ Sci Technol. 51: 11423-11430. PMID: 28858478
  3. Bisphenol A and its analogs bisphenol B, bisphenol F, and bisphenol S: Comparative in vitro and in vivo studies on the sperms and testicular tissues of rats.  |  Ullah, A., et al. 2018. Chemosphere. 209: 508-516. PMID: 29940534
  4. Bisphenol A analogues bisphenol B, bisphenol F, and bisphenol S induce oxidative stress, disrupt daily sperm production, and damage DNA in rat spermatozoa: a comparative in vitro and in vivo study.  |  Ullah, A., et al. 2019. Toxicol Ind Health. 35: 294-303. PMID: 30871434
  5. Occurrence, toxicity and endocrine disrupting potential of Bisphenol-B and Bisphenol-F: A mini-review.  |  Usman, A., et al. 2019. Toxicol Lett. 312: 222-227. PMID: 31136786
  6. Bisphenols B, E, F, and S and 4-cumylphenol induce lipid accumulation in mouse adipocytes similarly to bisphenol A.  |  Ramskov Tetzlaff, CN., et al. 2020. Environ Toxicol. 35: 543-552. PMID: 31820560
  7. Acute and sub-acute bisphenol-B exposures adversely affect sperm count and quality in adolescent male mice.  |  Ikhlas, S. and Ahmad, M. 2020. Chemosphere. 242: 125286. PMID: 31896186
  8. Amperometric Cytosensor for Studying Mitochondrial Interferences Induced by Plasticizers Bisphenol B and Bisphenol A.  |  Dragone, R., et al. 2020. Molecules. 25: PMID: 33171786
  9. Bisphenol B Exposure Disrupts Mouse Oocyte Meiotic Maturation in vitro Through Affecting Spindle Assembly and Chromosome Alignment.  |  Zhang, SX., et al. 2020. Front Cell Dev Biol. 8: 616771. PMID: 33392205
  10. Bisphenol B stimulates Leydig cell proliferation but inhibits maturation in late pubertal rats.  |  Li, Y., et al. 2021. Food Chem Toxicol. 153: 112248. PMID: 33940105
  11. Adverse effects of bisphenol B exposure on the thyroid and nervous system in early life stages of zebrafish.  |  Yang, Q., et al. 2021. Comp Biochem Physiol C Toxicol Pharmacol. 250: 109167. PMID: 34411698
  12. Bisphenol B disrupts testis differentiation partly via the estrogen receptor-mediated pathway and subsequently causes testicular dysgenesis in Xenopus laevis.  |  Li, HM., et al. 2022. Ecotoxicol Environ Saf. 236: 113453. PMID: 35390692
  13. Bisphenol B and bisphenol AF exposure enhances uterine diseases risks in mouse.  |  Wu, X., et al. 2023. Environ Int. 173: 107858. PMID: 36881955

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,2-Bis(4-hydroxyphenyl)butane, 5 g

sc-352249
5 g
$145.00

2,2-Bis(4-hydroxyphenyl)butane, 25 g

sc-352249A
25 g
$351.00