Date published: 2025-10-17

1-800-457-3801

SCBT Portrait Logo
Seach Input

2,2,2-Trifluoroethanol-d3 (CAS 77253-67-9)

0.0(0)
Write a reviewAsk a question

Application:
2,2,2-Trifluoroethanol-d3 is a useful deuterated and fluorinated ethanol
CAS Number:
77253-67-9
Molecular Weight:
103.06
Molecular Formula:
C2D3F3O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

2,2,2-Trifluoroethanol-d3 is a useful deuterated and fluorinated ethanol. This colorless liquid possesses a low boiling point and emits a sweet odor. It serves as a widely employed solvent for 1H NMR and 13C NMR spectroscopy. In NMR studies, the deuterium atoms allow for clearer signals for the compounds being analyzed. This is especially useful in the analysis of organic molecules, enabling researchers to study molecular structures, dynamics, and interactions with greater precision. In biochemical and biophysical research, 2,2,2-Trifluoroethanol-d3 is used to study protein folding and stability. Its trifluoroethanol moiety can interact with proteins, influencing their structure and dynamics.


2,2,2-Trifluoroethanol-d3 (CAS 77253-67-9) References

  1. Comparison of the structures of beta amyloid peptide (25-35) and substance P in trifluoroethanol/water solution.  |  Lee, S., et al. 1999. J Biomol Struct Dyn. 17: 381-91. PMID: 10563586
  2. Solvent effect on the isomeric equilibrium of carbohydrates: the superior ability of 2,2,2-trifluoroethanol for intramolecular hydrogen bond stabilization.  |  Molinaro, A., et al. 2001. J Am Chem Soc. 123: 12605-10. PMID: 11741425
  3. Morphology and structural properties of pH-responsive amphiphilic peptides.  |  Shera, JN., et al. 2010. J Nanosci Nanotechnol. 10: 7981-7. PMID: 21121287
  4. CD and NMR conformational studies of a peptide encompassing the Mid Loop interface of Ship2-Sam.  |  Mercurio, FA., et al. 2014. Biopolymers. 101: 1088-98. PMID: 24889333
  5. Design and activity of a cyclic mini-β-defensin analog: a novel antimicrobial tool.  |  Scudiero, O., et al. 2015. Int J Nanomedicine. 10: 6523-39. PMID: 26508857
  6. Exploring the therapeutic potential of an antinociceptive and anti-inflammatory peptide from wasp venom.  |  Galante, P., et al. 2023. Sci Rep. 13: 12491. PMID: 37528129
  7. Conformational Studies of Polyamides and Model Compounds Derived from Cyclic Dicarboxylic Acids and Spirodiamine  |  Yoshio Okamoto and C. G. Overberger. 1974,. Macromolecules. 7, 5: 614–618.
  8. NMR studies and conformations of asymmetric polyamides derived from cyclopropyl diacids and diamines  |   and C. G. Overberger, T. Nishiyama. February 1981. Journal of Polymer Science: Polymer Chemistry Edition. Volume19, Issue2: Pages 349-361.
  9. Vapour phase infrared studies of alcohols - I. Intramolecular interactions and self-association  |  , et al. 02 October 1973. Royal Society. Volume 335Issue 1600.
  10. Conformational Studies of Synthetic Polyethylene Glycol Bound Substance P and its Lower Analogues  |   and Piotr Koziej and Manfred Mutter. June 2, 2014. Zeitschrift für Naturforschung B. Volume 40 Issue 11.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,2,2-Trifluoroethanol-d3, 1 g

sc-256258
1 g
$210.00