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2,2,2-Tribromoethanol (CAS 75-80-9)

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Application:
2,2,2-Tribromoethanol is an organic compound used to anesthetize mice
CAS Number:
75-80-9
Purity:
≥97%
Molecular Weight:
282.76
Molecular Formula:
C2H3Br3O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,2,2-Tribromoethanol is an organic compound used to anesthetize mice. 2,2,2-Tribromoethanol is an ideal compound for Anesthesia because it functions deep and rapidly in mice and the recovery time is faster than other compounds. In addition, complementary chemicals can be added to the mouse with any major interactions. Studies indicate that 2,2,2-Tribromoethanol anesthetize mice within 5 minutes of injection and lasts about 25 minutes. This compound is thus an ideal tool during bilateral embryo transfers. Furthermore, the animals are mobile after 80-100 minutes following initial injection.


2,2,2-Tribromoethanol (CAS 75-80-9) References

  1. Tribromoethanol (Avertin) as an anaesthetic in mice.  |  Weiss, J. and Zimmermann, F. 1999. Lab Anim. 33: 192-3. PMID: 10780824
  2. A method to study preovulatory surges of gonadotropins.  |  Poletini, MO., et al. 2003. Brain Res Brain Res Protoc. 12: 41-8. PMID: 12928044
  3. A review of tribromoethanol anesthesia for production of genetically engineered mice and rats.  |  Meyer, RE. and Fish, RE. 2005. Lab Anim (NY). 34: 47-52. PMID: 16261153
  4. Kinetics of proinflammatory cytokines after intraperitoneal injection of tribromoethanol and a tribromoethanol/xylazine combination in ICR mice.  |  Cho, YJ., et al. 2011. Lab Anim Res. 27: 197-203. PMID: 21998608
  5. 2,2,2-Tribromoethanol phase-shifts the circadian rhythm of the liver clock in Per2::Luciferase knockin mice: lack of dependence on anesthetic activity.  |  Kubo, Y., et al. 2012. J Pharmacol Exp Ther. 340: 698-705. PMID: 22171092
  6. Repeated administration of tribromoethanol in C57BL/6NHsd mice.  |  Hill, WA., et al. 2013. J Am Assoc Lab Anim Sci. 52: 176-9. PMID: 23562101
  7. Increased anesthesia time using 2,2,2-tribromoethanol-chloral hydrate with low impact on mouse psychoacoustics.  |  Maheras, KJ. and Gow, A. 2013. J Neurosci Methods. 219: 61-9. PMID: 23856212
  8. Do fish perceive anaesthetics as aversive?  |  Readman, GD., et al. 2013. PLoS One. 8: e73773. PMID: 24086294
  9. Aqueous Flow Measured by Fluorophotometry in the Mouse.  |  Toris, CB., et al. 2016. Invest Ophthalmol Vis Sci. 57: 3844-52. PMID: 27447085
  10. Comparison of the anesthetic effects of 2,2,2-tribromoethanol on ICR mice derived from three different sources.  |  Lee, MR., et al. 2018. Lab Anim Res. 34: 270-278. PMID: 30671115
  11. A systematic study of injectable anesthetic agents in the brown anole lizard (Anolis sagrei ).  |  Rasys, AM., et al. 2020. Lab Anim. 54: 281-294. PMID: 31345120
  12. Nrf2 transcriptional activity in the mouse affects the physiological response to tribromoethanol.  |  Kopacz, A., et al. 2020. Biomed Pharmacother. 128: 110317. PMID: 32485566
  13. Adverse effects of tribromoethanol as used in the production of transgenic mice.  |  Zeller, W., et al. 1998. Lab Anim. 32: 407-13. PMID: 9807753

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,2,2-Tribromoethanol, 5 g

sc-238234
5 g
$32.00

2,2,2-Tribromoethanol, 25 g

sc-238234A
25 g
$98.00

2,2,2-Tribromoethanol, 100 g

sc-238234B
100 g
$272.00

2,2,2-Tribromoethanol, 500 g

sc-238234C
500 g
$1082.00

2,2,2-Tribromoethanol, 2.5 kg

sc-238234D
2.5 kg
$4727.00

2,2,2-Tribromoethanol, 5 kg

sc-238234E
5 kg
$9390.00

2,2,2-Tribromoethanol, 10 kg

sc-238234F
10 kg
$18366.00

If I order this item (2,2,2-Tribromoethanol, 25 g, sc-238234A) today, when can I receive it?

Asked by: Masami
Thank you for your question. For accurate availability, shipping and pricing information regarding our chemical products, please contact Customer Service.
Answered by: Tech Service
Date published: 2019-08-27
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Rated 5 out of 5 by from Various publications cite the use of theVarious publications cite the use of the organic compound 2,2,2-Tribromoethanol to anesthetize mice. -SCBT Publication Review
Date published: 2015-03-04
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2,2,2-Tribromoethanol is rated 5.0 out of 5 by 1.
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