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2-[1-(4-Piperonyl)piperazinyl]benzothiazole (CAS 155106-73-3)

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Application:
2-[1-(4-Piperonyl)piperazinyl]benzothiazole is a SR-4 agonist with moderate activity as a SR-3 antagonist
CAS Number:
155106-73-3
Molecular Weight:
353.4
Molecular Formula:
C19H19N3O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-[1-(4-Piperonyl)piperazinyl]benzothiazole is a research chemical utilized to study its interactions with biological targets, particularly in the field of neuroscience. It is useful for probing the mechanisms of neural signaling and for understanding the modulation of receptor systems within the nervous system. The research on this compound contributes to a broader comprehension of signal transduction processes and neural communication. Additionally, it serves as a reference point for the synthesis and investigation of new compounds with potential biological relevance. Its role in research helps to elucidate the complex pathways involved in neurological function and the potential discovery of novel modulators.


2-[1-(4-Piperonyl)piperazinyl]benzothiazole (CAS 155106-73-3) References

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  2. Diverse regulation of atrial natriuretic peptide secretion by serotonin receptor subtypes.  |  Cao, C., et al. 2003. Cardiovasc Res. 59: 360-8. PMID: 12909319
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  5. Roles of 5-hydroxytryptamine (5-HT) receptor subtypes in the inhibitory effects of 5-HT on C-fiber responses of spinal wide dynamic range neurons in rats.  |  Liu, FY., et al. 2007. J Pharmacol Exp Ther. 321: 1046-53. PMID: 17329553
  6. Decrease in the descending inhibitory 5-HT system in rats with spinal nerve ligation.  |  Liu, FY., et al. 2010. Brain Res. 1330: 45-60. PMID: 20230801
  7. Spinal 5-HT4 and 5-HT6 receptors contribute to the maintenance of neuropathic pain in rats.  |  Pineda-Farias, JB., et al. 2017. Pharmacol Rep. 69: 916-923. PMID: 28628851
  8. VB20B7, a novel 5-HT-ergic agent with gastrokinetic activity. II. Evaluation of the gastroprokinetic activity in rats and dogs.  |  García-Garayoa, E., et al. 1997. J Pharm Pharmacol. 49: 66-73. PMID: 9120773

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-[1-(4-Piperonyl)piperazinyl]benzothiazole, 5 mg

sc-203767
5 mg
$99.00