Date published: 2026-5-18

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2,1,3-Benzothiadiazol-4-yl isothiocyanate (CAS 109029-21-2)

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CAS Number:
109029-21-2
Molecular Weight:
193.25
Molecular Formula:
C7H3N3S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,1,3-Benzothiadiazol-4-yl isothiocyanate (BTITC) is an organosulfur compound that has found utility in diverse scientific applications. It presents as a white crystalline solid, readily soluble in polar solvents like methanol and ethanol. 2,1,3-Benzothiadiazol-4-yl isothiocyanate is a derivative of benzothiadiazole, an aromatic heterocyclic compound characterized by a sulfur atom within the ring structure. Remarkably, 2,1,3-Benzothiadiazol-4-yl isothiocyanate emerges as a potent inhibitor of a broad spectrum of enzymes, encompassing proteases, phosphatases, and kinases. Its inhibitory prowess stems from its ability to bind to the active sites of these enzymes, effectively impeding their catalytic activity. With its robust inhibitory properties against numerous enzymes, 2,1,3-Benzothiadiazol-4-yl isothiocyanate has been instrumental in biochemical investigations.


2,1,3-Benzothiadiazol-4-yl isothiocyanate (CAS 109029-21-2) References

  1. Optimization of a pipemidic acid autotaxin inhibitor.  |  Hoeglund, AB., et al. 2010. J Med Chem. 53: 1056-66. PMID: 20041668

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,1,3-Benzothiadiazol-4-yl isothiocyanate, 250 mg

sc-260129
250 mg
$364.00

2,1,3-Benzothiadiazol-4-yl isothiocyanate, 1 g

sc-260129A
1 g
$624.00