![2-[(5-Fluoresceinyl)aminocarbonyl]ethyl Methanethiosulfonate (CAS 351330-42-2) - chemical structure image](https://media.scbt.com/product/2--5-fluoresceinyl-aminocarbonylethyl-methanethiosulfonate-351330-42-2-structure_09_63_b_96366.jpg)
![2-[(5-Fluoresceinyl)aminocarbonyl]ethyl Methanethiosulfonate (CAS 351330-42-2) - chemical structure image](https://media.scbt.com/product/2--5-fluoresceinyl-aminocarbonylethyl-methanethiosulfonate-351330-42-2-structure_09_63_t_96366.jpg "Molecular structure of 2-[(5-Fluoresceinyl)aminocarbonyl]ethyl Methanethiosulfonate, CAS Number: 351330-42-2")
Molecular structure of 2-[(5-Fluoresceinyl)aminocarbonyl]ethyl Methanethiosulfonate, CAS Number: 351330-42-2
2-[(5-Fluoresceinyl)aminocarbonyl]ethyl Methanethiosulfonate (CAS 351330-42-2)
Alternate Names:
MTS-4-Fluorescein
Application:
2-[(5-Fluoresceinyl)aminocarbonyl]ethyl Methanethiosulfonate is a thiol-specific fluorescent probe
CAS Number:
351330-42-2
Molecular Weight:
513.54
Molecular Formula:
C24H19NO8S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
2-[(5-Fluoresceinyl)aminocarbonyl]ethyl Methanethiosulfonate is a thiol-specific fluorescent probe useful for ion channel and protein topology research. Recently available MTS-fluorophores may find application in the real-time monitoring of conformational changes due to their ability to change their fluorescence during a conformational change when coupled to introduced cysteines. Fluorescence lifetime may also yield information regarding distances and molecular motion in a protein molecule.
2-[(5-Fluoresceinyl)aminocarbonyl]ethyl Methanethiosulfonate (CAS 351330-42-2) References
- A pore segment in DEG/ENaC Na(+) channels. | Snyder, PM., et al. 1999. J Biol Chem. 274: 28484-90. PMID: 10497211
- Analysis of the pore structure of the influenza A virus M(2) ion channel by the substituted-cysteine accessibility method. | Shuck, K., et al. 2000. J Virol. 74: 7755-61. PMID: 10933681
- Site specific labeling of Rhodobacter sphaeroides reaction centers with dye probes for surface pH measurements. | Osváth, S., et al. 2001. Biochim Biophys Acta. 1505: 238-47. PMID: 11334788
- Influence of agonists and antagonists on the segmental motion of residues near the agonist binding pocket of the acetylcholine-binding protein. | Hibbs, RE., et al. 2006. J Biol Chem. 281: 39708-18. PMID: 17068341
- Structural implications of fluorescence quenching in the Shaker K+ channel. | Cha, A. and Bezanilla, F. 1998. J Gen Physiol. 112: 391-408. PMID: 9758859
- Inhibition of the epithelial Na+ channel by interaction of Nedd4 with a PY motif deleted in Liddle's syndrome. | Goulet, CC., et al. 1998. J Biol Chem. 273: 30012-7. PMID: 9792722
- Protons activate brain Na+ channel 1 by inducing a conformational change that exposes a residue associated with neurodegeneration. | Adams, CM., et al. 1998. J Biol Chem. 273: 30204-7. PMID: 9804777
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-[(5-Fluoresceinyl)aminocarbonyl]ethyl Methanethiosulfonate, 10 mg | sc-216155 | 10 mg | $337.00 |