Date published: 2025-12-6

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(1R,4S)-N-Desmethyl Sertraline Hydrochloride (CAS 675126-08-6)

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Alternate Names:
Dasotraline hydrochloride
Application:
(1R,4S)-N-Desmethyl Sertraline Hydrochloride is A metabolite of Sertraline
CAS Number:
675126-08-6
Molecular Weight:
328.66
Molecular Formula:
C16H16Cl3N
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(1R,4S)-N-Desmethyl Sertraline Hydrochloride is primarily used in research to understand its kinetics and metabolism relative to its parent compound. It is often studied to elucidate the metabolic pathway of sertraline, as it is a major metabolite formed in the liver by demethylation. Investigations include examining its interaction with neurotransmitter systems and its potential metabolic effects in various in vitro systems. Moreover, research involving (1R,4S)-N-Desmethyl Sertraline Hydrochloride typically aims to determine its binding affinity to neurotransmitter transporters and receptors compared to sertraline. The chemical is also of interest in environmental research, where its stability and degradation in aquatic systems are assessed.


(1R,4S)-N-Desmethyl Sertraline Hydrochloride (CAS 675126-08-6) References

  1. Simultaneous determination of polar pharmaceuticals and personal care products in biological organs and tissues.  |  Tanoue, R., et al. 2014. J Chromatogr A. 1355: 193-205. PMID: 24958034

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(1R,4S)-N-Desmethyl Sertraline Hydrochloride, 1 mg

sc-206300
1 mg
$337.00