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1H-Tetrazole-5-acetic acid (CAS 21743-75-9)

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Alternate Names:
2-(1H-1,2,3,4-Tetrazol-5-yl)acetic acid
CAS Number:
21743-75-9
Purity:
96%
Molecular Weight:
128.09
Molecular Formula:
C3H4N4O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1H-Tetrazole-5-acetic acid (HTA) is an important organic compound that has been used in a wide range of scientific research applications, from biochemistry and physiology to laboratory experiments. Studies have demonstrated that 1H-Tetrazole-5-acetic acid can influence cellular metabolism, cell development, and growth. Additionally, its impact extends to the immune system and cancer development. Moreover, this compound has been found to modulate gene expression and regulate the production of various proteins. 1H-Tetrazole-5-acetic acid has been used in the synthesis of other chemical compounds as well as to investigate the biochemical and physiological effects of various compounds.


1H-Tetrazole-5-acetic acid (CAS 21743-75-9) References

  1. Synthesis and characterization of silver and gold nanoparticles in ionic liquid.  |  Singh, P., et al. 2009. Spectrochim Acta A Mol Biomol Spectrosc. 73: 218-20. PMID: 19272833
  2. Energetic high-nitrogen compounds: 5-(trinitromethyl)-2H-tetrazole and -tetrazolates, preparation, characterization, and conversion into 5-(dinitromethyl)tetrazoles.  |  Haiges, R. and Christe, KO. 2013. Inorg Chem. 52: 7249-60. PMID: 23725011
  3. Tetrazole-based, anhydrous proton exchange membranes for fuel cells.  |  Song, MK., et al. 2014. Adv Mater. 26: 1277-82. PMID: 24591010
  4. The effects of second electron acceptor group on the performance of tetrazole-based nanocrystalline TiO2 sensitizers in DSSCs.  |  Jafari Chermahini, Z., et al. 2017. Spectrochim Acta A Mol Biomol Spectrosc. 178: 79-85. PMID: 28167362
  5. Enhancing Energetic Performance of Multinuclear Ag(I)-Cluster MOF-Based High-Energy-Density Materials by Thermal Dehydration.  |  Ma, X., et al. 2019. ACS Appl Mater Interfaces. 11: 9233-9238. PMID: 30762334
  6. Combination of Energetic Tetrazole and Triazole: Promising Materials with Exceptional Stability and Low Mechanical Sensitivity as Propellants and Gas Generators.  |  Liu, Y., et al. 2023. ACS Appl Mater Interfaces. 15: 15311-15320. PMID: 36926825
  7. Synthesis of new dyes containing double tetrazole groups for sensitization of TiO2 nanoparticles in dye-sensitized solar cells  |  , et al. (2017). Journal of the Iranian Chemical Society. volume 14,: pages 1549–1556.
  8. 1D Structure Sodium Coordination Anion based on [5-(Dinitromethylene)-4,5-dihydro-1H-tetrazole]: Syntheses, Structures, and Thermal Behavior  |   and Le Wu, Jian-Guo Zhang, Jin-Ting Wu, Xin Yin, Piao He. September 2016. Zeitschrift für anorganische und allgemeine Chemie. Volume642, Issue18: Pages 949-952.
  9. Tetrazole 5-Acetic Acid Catalyzed Synthesis and Photophysical Study of 2-Aryl-2,3-dihydroquinolin-4(1H)-ones  |  , et al. 2019,. Letters in Organic Chemistry,. Volume 16, Number 3,: pp. 176-184(9).
  10. Accelerated thermal decomposition of ammonium perchlorate by electron transfer from dinuclear rare-earth EMOFs☆  |  X Gao, B Li, X Zhu, R Wang, Y Yang, J Liang… - Journal of Solid State …, 2023 - Elsevier. August 2023,. Journal of Solid State Chemistry. Volume 324,: 124097.
  11. Tetrazole-functionalized microcrystalline cellulose: A promising biopolymer for advanced energetic materials  |  AF Tarchoun, D Trache, TM Klapötke… - Chemical Engineering …, 2020 - Elsevier. 15 November 2020,. Chemical Engineering Journal. Volume 400,: 125960.
  12. Bioactive mixed-ligand zinc(II) complexes with 1H-tetrazole-5-acetic acid and oligopyridine derivatives  |  EA Ermakova, JA Golubeva, KS Smirnova… - Polyhedron, 2023 - Elsevier. 15 January 2023,. Polyhedron. Volume 230,: 116213.
  13. Cytotoxic mixed-ligand copper(ii) complexes with 1H-tetrazole-5-acetic acid and oligopyridine derivatives†  |  Ekaterina A. Ermakova, ORCID logo a Yuliya A. Golubeva, ORCID logo a Ksenia S. Smirnova, ORCID logo a Lyubov S. Klyushova, ORCID logo b Alexey S. Berezin,a Leonid N. Fetisov,c Alexandra E. Svyatogorova,c Natalia O. Andros,c Alexander A. Zubenkoc and Elizaveta V. Lider ORCID logo *a. Issue 19, 2023. New J. Chem.,.,47,: 9472-9482.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1H-Tetrazole-5-acetic acid, 1 g

sc-223202
1 g
$56.00

1H-Tetrazole-5-acetic acid, 5 g

sc-223202A
5 g
$168.00