Date published: 2025-10-17

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1H-Pyrazole-1-carboxamidine Hydrochloride (CAS 4023-02-3)

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Application:
1H-Pyrazole-1-carboxamidine Hydrochloride is a reagent used for peptide synthesis and chemically specific guanylation of amines
CAS Number:
4023-02-3
Purity:
>99%
Molecular Weight:
146.58
Molecular Formula:
C4H7ClN4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Reagent for the chemically specific guanylation of sterically unhindered primary and secondary aliphatic amines in an efficient manner under mild conditions. Also used as a reagent in peptide synthesis.


1H-Pyrazole-1-carboxamidine Hydrochloride (CAS 4023-02-3) References

  1. Effects of ethanol and of alcohol dehydrogenase inhibitors on the reduction of N-acetylaspartate levels of brain in mice in vivo: a search for substances that may have therapeutic value in the treatment of Canavan disease.  |  Baslow, MH., et al. 2000. J Inherit Metab Dis. 23: 684-92. PMID: 11117430
  2. 1H-pyrazole-1-carboxamidines: new inhibitors of nitric oxide synthase.  |  Lee, Y., et al. 2000. Bioorg Med Chem Lett. 10: 2771-4. PMID: 11133088
  3. Guanidylated hollow fiber membranes based on brominated poly (2,6-dimethyl-1,4-phenylene oxide) (BPPO) for gold sorption from acid solutions.  |  Ran, J., et al. 2012. J Hazard Mater. 241-242: 63-72. PMID: 23046695
  4. Comprehensive Analysis of Protein N-Terminome by Guanidination of Terminal Amines.  |  Sun, M., et al. 2020. Anal Chem. 92: 567-572. PMID: 31846294
  5. Synthesis of new 1,2,3-triazolo-nucleoside analogues with 2-propargylamino pyrimidines via click reactions.  |  Ay, E. 2023. Nucleosides Nucleotides Nucleic Acids. 42: 191-205. PMID: 36047982
  6. Polysaccharide-Based Supramolecular Hydrogel Coatings with Corrosion Barrier Zone for Protection of Patina Bronze.  |  Zhang, J., et al. 2023. Polymers (Basel). 15: PMID: 37631414
  7. Anion Binding to Ammonium and Guanidinium Hosts: Implications for the Reverse Hofmeister Effects Induced by Lysine and Arginine Residues.  |  Jordan, JH., et al. 2024. J Org Chem. 89: 6877-6891. PMID: 38662908
  8. Carbon Nanodisks Decorated with Guanidinylated Hyperbranched Polyethyleneimine Derivatives as Efficient Antibacterial Agents.  |  Lyra, KM., et al. 2024. Nanomaterials (Basel). 14: PMID: 38668171
  9. Intracellular delivery and deep tissue penetration of nucleoside triphosphates using photocleavable covalently bound dendritic polycations.  |  Ma, J., et al. 2024. Chem Sci. 15: 6478-6487. PMID: 38699261
  10. Inhibition of nitric oxide synthase with pyrazole-1-carboxamidine and related compounds.  |  Southan, GJ., et al. 1997. Biochem Pharmacol. 54: 409-17. PMID: 9278100

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1H-Pyrazole-1-carboxamidine Hydrochloride, 2.5 g

sc-220659
2.5 g
$100.00