Date published: 2025-12-15

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1H-Perfluorooctane (CAS 335-65-9)

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Alternate Names:
1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8-Heptadecafluorooctane
Application:
1H-Perfluorooctane is a fluorocarbon liquid
CAS Number:
335-65-9
Purity:
≥95%
Molecular Weight:
420.07
Molecular Formula:
C8HF17
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1H-Perfluorooctane, is a fluorinated hydrocarbon compound that has garnered significant interest in recent years due to its potential applications. The synthesis of 1H-Perfluorooctane involves a two-step process. Initially, a fluorinated alcohol is synthesized, followed by its reaction with a fluorinated acid in the second step. This reaction leads to the formation of 1H-Perfluorooctane along with a by-product that can be separated and removed. This two-step synthesis process has proven to be more efficient compared to other methods employed. 1H-Perfluorooctane has found wide-ranging applications. It has been utilized in studies involving molecular dynamics, serving as a solvent for chemical reactions and as a lubricant in biomedical devices.


1H-Perfluorooctane (CAS 335-65-9) References

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  2. Electrochemical treatment of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) in groundwater impacted by aqueous film forming foams (AFFFs).  |  Schaefer, CE., et al. 2015. J Hazard Mater. 295: 170-5. PMID: 25909497
  3. Biological Cleavage of the C–P Bond in Perfluoroalkyl Phosphinic Acids in Male Sprague-Dawley Rats and the Formation of Persistent and Reactive Metabolites.  |  Joudan, S., et al. 2017. Environ Health Perspect. 125: 117001. PMID: 29135439
  4. Insights into Uptake, Translocation, and Transformation Mechanisms of Perfluorophosphinates and Perfluorophosphonates in Wheat (Triticum aestivum L.).  |  Zhou, J., et al. 2020. Environ Sci Technol. 54: 276-285. PMID: 31795634
  5. Comparison of Perfluorocarbon Liquids Cytotoxicity Tests: Direct Contact Versus the Test on Liquid Extracts.  |  Gatto, C., et al. 2023. ACS Omega. 8: 365-372. PMID: 36643447
  6. PFAS Biotransformation Pathways: A Species Comparison Study.  |  Kolanczyk, RC., et al. 2023. Toxics. 11: PMID: 36668800
  7. Characterization of PFAS air emissions from thermal application of fluoropolymer dispersions on fabrics.  |  Wickersham, LC., et al. 2023. J Air Waste Manag Assoc. 1-20. PMID: 36947591
  8. Perfluorinated and partially fluorinated organic compounds. Preparation, characterization and application  |  H. Meinert. 1994. 82: 201-214.
  9. Perfluorooctyl substituted triphenylphosphites as ligands for hydroformylation of higher olefins in fluorocarbon/hydrocarbon biphasic medium  |  Thomas Mathivet a, Éric Monflier b, Yves Castanet a, André Mortreux a, Jean-Luc Couturier c. 2002. Comptes Rendus Chimie. 5: 417-424.
  10. Hydroformylation of higher olefins by rhodium/tris-((1H,1H,2H,2H-perfluorodecyl)phenyl)phosphites complexes in a fluorocarbon/hydrocarbon biphasic medium: effects of fluorinated groups on the activity and stability of the catalytic system  |  Thomas Mathivet a, Eric Monflier b, Yves Castanet c, André Mortreux c, Jean-Luc Couturier d. 2002. Tetrahedron. 58: 3877-3888.
  11. Dimerisation of butadiene catalyzed by nickel–tris[(1H,1H,2H,2H-perfluorodecyl)phenyl]phosphites complexes in fluorocarbon–hydrocarbon biphasic medium  |  Renata Matusiak, Yves Castanet, André Mortreux. 2004. Journal of Molecular Catalysis A: Chemical. 224: 217-223.
  12. Chapter 10 - Biocompatibility of Highly Fluorinated Liquids Used in Ophthalmic Surgery  |  Dirk‐Henning Menz 1, Joachim H. Dresp 2. 2008. Fluorine and Health. 421-445.
  13. Fabrication and characterization of PVDF-CTFE/SiO2 electrospun nanofibrous membranes with micro and nano-rough structures for efficient oil-water separation  |  Wanzheng Ren a, Jian Pan a b, Wenqiang Gai a, Xinyu Pan a, Haimei Chen a, Jiao Li a, Lilan Huang a. 2023. Separation and Purification Technology. 311.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1H-Perfluorooctane, 1 g

sc-223200
1 g
$63.00

1H-Perfluorooctane, 5 g

sc-223200A
5 g
$182.00