Date published: 2026-2-2

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1H-Imidazole-4-sulfonyl chloride (CAS 58767-51-4)

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Alternate Names:
Imidazole-4-sulfonyl chloride; 4-Chlorosulfonylimidazole
CAS Number:
58767-51-4
Molecular Weight:
166.59
Molecular Formula:
C3H3ClN2O2S
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1H-Imidazole-4-sulfonyl chloride is a compound that functions as a sulfonylating agent in organic synthesis. It acts as a source of the sulfonyl group, which can be transferred to nucleophilic substrates, leading to the formation of sulfonyl derivatives. In this capacity, it participates in the modification of organic molecules, enabling the introduction of the sulfonyl functionality into various chemical structures. The mechanism of action involves the reaction of 1H-Imidazole-4-sulfonyl chloride with nucleophilic substrates, resulting in the substitution of the chloride group with the sulfonyl group.


1H-Imidazole-4-sulfonyl chloride (CAS 58767-51-4) References

  1. Structure-Based Discovery of a Series of 5H-Pyrrolo[2,3-b]pyrazine FGFR Kinase Inhibitors.  |  Jiang, A., et al. 2018. Molecules. 23: PMID: 29562726
  2. Discovery of a series of dimethoxybenzene FGFR inhibitors with 5H-pyrrolo[2,3-b]pyrazine scaffold: structure-activity relationship, crystal structural characterization and in vivo study.  |  Wei, P., et al. 2019. Acta Pharm Sin B. 9: 351-368. PMID: 30972282

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1H-Imidazole-4-sulfonyl chloride, 1 g

sc-304188
1 g
$114.00