1H-Imidazol-4-ylacetic acid (CAS 645-65-8)
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1H-Imidazol-4-ylacetic acid is a compound that is of significant interest in the field of organic and biochemical research due to its imidazole ring, a structural motif common in many biologically active molecules. This compound is frequently used as a starting material or intermediate in the synthesis of heterocyclic compounds. The presence of the carboxylic acid group allows for the formation of amides and esters, making 1H-Imidazol-4-ylacetic acid versatile for chemical modifications. It is also studied for its potential role in the design of enzyme inhibitors, as the imidazole ring can mimic the transition states of enzymatic reactions or bind to catalytic residues within the enzyme′s active site. Furthermore, its use in the preparation of chelating agents that can bind to metal ions is another area of application, which is relevant in both analytical chemistry and the development of metal-based compounds.
1H-Imidazol-4-ylacetic acid (CAS 645-65-8) References
- Development of imidazole alkanoic acids as mGAT3 selective GABA uptake inhibitors. | Hack, S., et al. 2011. Eur J Med Chem. 46: 1483-98. PMID: 21353350
- Synthesis and biological evaluation of a series of N-alkylated imidazole alkanoic acids as mGAT3 selective GABA uptake inhibitors. | Kerscher-Hack, S., et al. 2016. Eur J Med Chem. 124: 852-880. PMID: 27654218
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1H-Imidazol-4-ylacetic acid, 500 mg | sc-304185 | 500 mg | $281.00 |