Molecular structure of 19(R)-hydroxy Prostaglandin B2
19(R)-hydroxy Prostaglandin B2
Alternate Names:
19(R)-OH PGB2; 9-oxo-15S, 19R-dihydroxy-prosta-5Z, 8(12), 13E-trien-1-oicacid
Application:
19(R)-hydroxy Prostaglandin B2 is an internal standard in extractions and HPLC
Molecular Weight:
350.50
Molecular Formula:
C20H30O5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Base treatment of human seminal plasma extracts converts 19-hydroxy PGE compounds present in sample into corresponding PGB compounds, generating strong conjugated dienone chromophores. This method has been used to provide a rapid, UV-based analytical method for PGE quantitation. Due to its chemical stability and strong UV absorbance at 278 nm, 19(R)-hydroxy PGB2 is also used as an internal standard in extractions and HPLC to determine recovery of arachidonic acid metabolites(1,2,3).
19(R)-hydroxy Prostaglandin B2 References
1 Antoine, C., Murphy, R.C., Henson, P.M., et al. Time-dependent utilization of platelet arachidonic acid by the neutrophil in formation of 5-lipoxygenase products in platelet-neutrophil co-incubations. Biochim Biophys Acta 1128 139-146 (1992). 2 Borgeat, P., Picard, S. 19-Hydroxyprostaglandin B2 as an internal standard for on-line extraction-high-performance liquid chromatography analysis of lipoxygenase products. Anal Biochem 171 283-289 (1988). 3 Surette, M.E., Odeimat, A., Palmantier, R., et al. Reverse-phase high-performance liquid chromatography analysis of arachidonic acid metabolites in plasma after stimulation of whole blood ex vivo. Anal Biochem 216 392-400 (1994).Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
19(R)-hydroxy Prostaglandin B2, 50 µg | sc-223190 | 50 µg | $74.00 | |||
19(R)-hydroxy Prostaglandin B2, 100 µg | sc-223190A | 100 µg | $140.00 |