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Leukotrienes comprise a family of endogenous metabolites of certain fatty acids and are related to thromboxanes and prostaglandins. They are potent eicosanoid lipid mediators that play numerous roles in inflammation, immunological functions and maintaining biological homeostasis. Leukotrienes possess a conjugated triene structure which gives them their name. They are generally isolated from leukocytes and primarily act through specific G protein-coupled receptors. 18-carboxy dinor Leukotriene B4 (18-carboxy dinor LTB4) is a β-oxidation metabolite of LTB4. LTB4 has been shown to be rapidly metabolized in the liver to 20-carboxy LTB4, which then undergoes β-oxidation to 18-carboxy dinor LTB4.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
18-carboxy dinor Leukotriene B4, 25 µg | sc-205066 | 25 µg | $176.00 | |||
18-carboxy dinor Leukotriene B4, 50 µg | sc-205066A | 50 µg | $337.00 |