Molecular structure of 17β-Neriifolin, CAS Number: 466-07-9
17β-Neriifolin (CAS 466-07-9)
Alternate Names:
(3β,5β)-3-[(6-deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-card-20(22)-enolide
CAS Number:
466-07-9
Molecular Weight:
534.68
Molecular Formula:
C30H46O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
17β-Neriifolin, also known as Neriifolin, is a cardiac glycoside compound that is naturally found in the leaves of the Nerium oleander plant, also known as the oleander plant. Its anti-cancer properties have been studied, and it may act to induce cell death in cancer cells through its ability to inhibit the Na+/K+-ATPase enzyme. This enzyme is essential for maintaining the balance of sodium and potassium ions in cells, and by inhibiting it, 17β-Neriifolin can disrupt cell function and cause cell death.
17β-Neriifolin (CAS 466-07-9) References
- New cytotoxic cardenolide glycoside from the seeds of Cerbera manghas. | Cheenpracha, S., et al. 2004. Chem Pharm Bull (Tokyo). 52: 1023-5. PMID: 15305009
- Acaricidal activity against Panonychus citri and active ingredient of the mangrove plant Cerbera manghas. | Deng, Y., et al. 2014. Nat Prod Commun. 9: 1265-8. PMID: 25918788
- 17β-neriifolin from unripe fruits of Cerbera manghas suppressed cell proliferation via the inhibition of HOXA9-dependent transcription and the induction of apoptosis in the human AML cell line THP-1. | Takase, S., et al. 2023. J Nat Med. 77: 180-187. PMID: 36266527
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
17β-Neriifolin, 5 mg | sc-478140 | 5 mg | $360.00 | |||
17β-Neriifolin, 50 mg | sc-478140A | 50 mg | $2711.00 |