Date published: 2025-10-2

1-800-457-3801

SCBT Portrait Logo
Seach Input

17a-Hydroxyprogesterone (CAS 68-96-2)

0.0(0)
Write a reviewAsk a question

Application:
17a-Hydroxyprogesterone is an antiestrogen compound
CAS Number:
68-96-2
Purity:
≥97%
Molecular Weight:
330.46
Molecular Formula:
C21H30O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

17a-Hydroxyprogesterone is a steroid hormone that acts as an intermediate in the biosynthesis of other steroid hormones, such as cortisol and androstenedione. It is involved in the regulation of the menstrual cycle and plays a role in the development of the female reproductive system. 17a-Hydroxyprogesterone functions as a precursor in the synthesis of other important hormones, contributing to the hormonal balance and regulation. At the molecular level, it interacts with specific enzymes and receptors to initiate the synthesis of cortisol and androstenedione, thereby influencing various physiological processes. Its mechanism of action involves binding to specific receptors and activating signaling pathways that ultimately lead to the production of other steroid hormones.


17a-Hydroxyprogesterone (CAS 68-96-2) References

  1. Ovulation rate and litter size in gilts immunized against androstenedione and 17alpha-hydroxyprogesterone.  |  Kreider, DL., et al. 2001. J Anim Sci. 79: 1691-6. PMID: 11465355
  2. Low basal androstenedione levels plus augmented 17alpha-hydroxyprogesterone and low dehydroepiandrosterone sulfate responses to adrenocorticotropic hormone stimulation in patients with adrenal incidentaloma.  |  Ozgen, AG., et al. 2001. Endocr Pract. 7: 448-53. PMID: 11747281
  3. Lower adrenocortical and adrenomedullary responses to hypoglycemia in premenopausal women with systemic sclerosis.  |  Imrich, R., et al. 2006. J Rheumatol. 33: 2235-41. PMID: 17086608
  4. Molecular analysis of the AR and SRD5A2 genes in patients with 46,XY disorders of sex development.  |  Choi, JH., et al. 2008. J Pediatr Endocrinol Metab. 21: 545-53. PMID: 18717241
  5. Congenital adrenal hyperplasia due to 21-hydroxylase deficiency - management in adults.  |  Ambroziak, U., et al. 2010. Endokrynol Pol. 61: 142-55. PMID: 20205117
  6. [Congenital adrenal hyperplasia due to 21-hydroxylase deficiency--management in adults].  |  Ambroziak, U., et al. 2010. Endokrynol Pol. 61 Suppl 1: 7-21. PMID: 22127631
  7. Prevention of preterm delivery with compounded 17a-hydroxyprogesterone caproate.  |  Reed-Kane, D. and Kirschbaum, K. 2006. Int J Pharm Compd. 10: 165-71. PMID: 23974228
  8. Analysis by LC-MS/MS of endogenous steroids from human serum, plasma, endometrium and endometriotic tissue.  |  Häkkinen, MR., et al. 2018. J Pharm Biomed Anal. 152: 165-172. PMID: 29414008
  9. Diurnal variation of steroid hormones and their reference intervals using mass spectrometric analysis.  |  Parikh, TP., et al. 2018. Endocr Connect. 7: 1354-1361. PMID: 30400040
  10. Progesterone Supplementation for the Prevention of Preterm Birth: Provider Practice in Wisconsin.  |  Hoppe, K., et al. 2019. WMJ. 118: 126-131. PMID: 31682748
  11. The efficiency of 17a hydroxyprogesterone in the prevention of preterm labour irrespective of administration route: Systematic review metanalysis.  |  Nori, W., et al. 2021. J Pak Med Assoc. 71(Suppl 9): S65-S69. PMID: 35130263
  12. Daughters of polycystic ovary syndrome pregnancies and androgen levels in puberty: a Meta-analysis.  |  Valsamakis, G., et al. 2022. Gynecol Endocrinol. 38: 822-830. PMID: 36104976
  13. Sweet Taste Receptor T1R3 Expressed in Leydig Cells Is Closely Related to Homeostasis of the Steroid Hormone Metabolism Profile.  |  Wang, W., et al. 2023. J Agric Food Chem. 71: 7791-7802. PMID: 37186581

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

17a-Hydroxyprogesterone, 1 g

sc-204614
1 g
$59.00

17a-Hydroxyprogesterone, 5 g

sc-204614A
5 g
$102.00