17(S)-HDoHE
Molecular Weight:
344.5
Molecular Formula:
C22H32O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
This is a primary mono-oxygenation product of docosahexaenoic acid, which is in human whole blood, human leukocytes, and murine brain(1). It serves as a precursor to 17(S)-resolvins and has intrinsic biological activity, such as the inhibition of TNFα-induced leukocyte trafficking to the murine air pouch and inhibition of TNFα-induced interleukin-1β expression in human glioma cells(1).
17(S)-HDoHE References
1 Hong, S., Gronert, K., Devchand, P.R., et al. Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation. J Biol Chem 278(17) 14677-14687 (2003).Inhibitor of:
TNF alpha.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
17(S)-HDoHE, 25 µg | sc-220654 | 25 µg | $120.00 | |||
17(S)-HDoHE, 50 µg | sc-220654A | 50 µg | $228.00 |