Molecular structure of 17-Oxo Dexamethasone, CAS Number: 1880-61-1
17-Oxo Dexamethasone (CAS 1880-61-1)
See product citations (1)
Alternate Names:
9-Fluoro-11-hydroxy-16-methyl-(11β,16α ) Androsta-1,4-diene-3,17-dione
Application:
17-Oxo Dexamethasone is a dexamethasone metabolite
CAS Number:
1880-61-1
Purity:
98%
Molecular Weight:
332.41
Molecular Formula:
C20H25FO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
17-Oxo Dexamethasone is a metabolite of the synthetic antiinflammatory glucocorticoid Dexamethasone (sc-29059). 17-Oxo Dexamethasone is produced by oxidative cleavage of the side chain on Dexamethasone. Metabolites of Dexamethasone like 17-Oxo Dexamethasone are used as markers for detection of Dexamethasone in urinary samples and in unknown veterinary and human drug formulations.
17-Oxo Dexamethasone (CAS 1880-61-1) References
- Cushing's syndrome, nodular adrenal hyperplasia and virilizing carcinoma. | Anderson, DC., et al. 1978. Clin Endocrinol (Oxf). 9: 1-14. PMID: 209918
- Occurrence, Fate, Effects, and Risks of Dexamethasone: Ecological Implications Post-COVID-19. | Musee, N., et al. 2021. Int J Environ Res Public Health. 18: PMID: 34769808
- Dexamethasone-loaded keratin films for ocular surface reconstruction. | Schwab, R. and Reichl, S. 2022. J Mater Sci Mater Med. 33: 29. PMID: 35244790
- Applications of chromatographic and spectrometric techniques to the study of dexamethasone related compounds | Gaignage, P., Lognay, G., Marlier, M., Severin, M., & Dreze, P. 1989. Chromatographia. 28: 623-630.
- Isolation, identification, and characterization of 17-oxo dexamethasone, an oxidative degradation impurity of dexamethasone using flash chromatography and NMR/HRMS/IR | Ummiti, K., Vakkala, S., Panuganti, V., & Annarapu, M. R. 2014. Journal of Liquid Chromatography & Related Technologies. 37(17): 2403-2419.
- Formation of bioactive transformation products during glucocorticoid chlorination | Pflug, N. C., Kupsco, A., Kolodziej, E. P., Schlenk, D., Teesch, L. M., Gloer, J. B., & Cwiertny, D. M. 2017. Environmental Science: Water Research & Technology. 3(3): 450-461.
- A step forward in the detection of byproducts of anthropogenic organic micropollutants in chlorinated water | Postigo, C., Gil-Solsona, R., Herrera-Batista, M. F., Gago-Ferrero, P., Alygizakis, N., Ahrens, L., & Wiberg, K. 2021. Trends in Environmental Analytical Chemistry. 32: e00148.
- Dexamethasone degradation in aqueous medium by a thermally activated persulfate system: Kinetics and transformation products | Arvaniti, O. S., Ioannidi, A. Α., Politi, A., Miserli, K., Konstantinou, I., Mantzavinos, D., & Frontistis, Z. 2022. Journal of Water Process Engineering. 49: 103134.
- Digital light processing and drug stability of Dexamethasone-loaded implant prototypes for medical treatment of the inner ear | Mau, R., Schick, P., Matin-Mann, F., Gao, Z., Labrador, D. A., John, S.,.. & Seitz, H. 2022. Transactions on Additive Manufacturing Meets Medicine. 4(1): 666-666.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
17-Oxo Dexamethasone, 2.5 mg | sc-208877 | 2.5 mg | $312.00 |