Molecular structure of 17-ODYA (17-Octadecynoic acid), CAS Number: 34450-18-5
17-ODYA (17-Octadecynoic acid) (CAS 34450-18-5)
See product citations (9)
Application:
17-ODYA (17-Octadecynoic acid) is a potent suicide inhibitor of LTB4 ω-oxidase
CAS Number:
34450-18-5
Purity:
≥98%
Molecular Weight:
280.45
Molecular Formula:
C18H32O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
17-ODYA (17-Octadecynoic acid) is a potent suicide inhibitor of CYP4F3 (leukotriene B4 (LTB4) omega-oxidase) (IC50
17-ODYA (17-Octadecynoic acid) (CAS 34450-18-5) References
- 17-Octadecynoic acid improves contractile response to angiotensin II by releasing vasocontrictor prostaglandins. | Jerez, S., et al. 2012. Prostaglandins Other Lipid Mediat. 97: 36-42. PMID: 21839852
- Arachidonic acid inhibits Na⁺-K⁺-ATPase via cytochrome P-450, lipoxygenase and protein kinase C-dependent pathways in sheep pulmonary artery. | Singh, TU., et al. 2012. Vascul Pharmacol. 56: 84-90. PMID: 22155164
- Development of amphiphilic, enzymatically-degradable PEG-peptide conjugate as cell crosslinker for spheroid formation. | Rao, Z., et al. 2013. Colloids Surf B Biointerfaces. 101: 223-7. PMID: 23010023
- Controlled Assembly of Biocompatible Metallic Nanoaggregates Using a Small Molecule Crosslinker. | Van Haute, D., et al. 2015. Adv Mater. 27: 5158-64. PMID: 26208123
- Gellan gum microspheres crosslinked with trivalent ion: effect of polymer and crosslinker concentrations on drug release and mucoadhesive properties. | Boni, FI., et al. 2016. Drug Dev Ind Pharm. 42: 1283-90. PMID: 26616390
- Leukotriene B4 omega-hydroxylase in human polymorphonuclear leukocytes. Suicidal inactivation by acetylenic fatty acids. | Shak, S., et al. 1985. J Biol Chem. 260: 13023-8. PMID: 2997155
- The Essential Role of 17-Octadecynoic Acid in the Pathogenesis of Periapical Abscesses. | Altaie, AM., et al. 2023. J Endod. 49: 169-177.e3. PMID: 36528175
- Effects of 17-octadecynoic acid, a suicide-substrate inhibitor of cytochrome P450 fatty acid omega-hydroxylase, on renal function in rats. | Zou, AP., et al. 1994. J Pharmacol Exp Ther. 268: 474-81. PMID: 8301590
- NO/PGI2-independent vasorelaxation and the cytochrome P450 pathway in rabbit carotid artery. | Dong, H., et al. 1997. Br J Pharmacol. 120: 695-701. PMID: 9051310
- P450 arachidonate metabolites mediate bradykinin-dependent inhibition of NaCl transport in the rat thick ascending limb. | Grider, JS., et al. 1997. Can J Physiol Pharmacol. 75: 91-6. PMID: 9114929
- Cytochrome P-450 metabolites mediate norepinephrine-induced mitogenic signaling. | Uddin, MR., et al. 1998. Hypertension. 31: 242-7. PMID: 9453310
- Effects of intrarenal infusion of 17-octadecynoic acid on renal antihypertensive mechanisms in anesthetized rabbits. | Evans, RG., et al. 1998. Am J Hypertens. 11: 803-12. PMID: 9683041
- Nitric oxide-20-hydroxyeicosatetraenoic acid interaction in the regulation of K+ channel activity and vascular tone in renal arterioles. | Sun, CW., et al. 1998. Circ Res. 83: 1069-79. PMID: 9831701
Inhibitor of:
CYP2J2, CYP4A11, CYP4F3, and EP3.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
17-ODYA (17-Octadecynoic acid), 1 mg | sc-200488 | 1 mg | $42.00 | |||
17-ODYA (17-Octadecynoic acid), 5 mg | sc-200488C | 5 mg | $132.00 | |||
17-ODYA (17-Octadecynoic acid), 10 mg | sc-200488A | 10 mg | $214.00 | |||
17-ODYA (17-Octadecynoic acid), 100 mg | sc-200488B | 100 mg | $1438.00 |