Molecular structure of 17-DMAG, Hydrochloride Salt, CAS Number: 467214-21-7
17-DMAG, Hydrochloride Salt (CAS 467214-21-7)
Alternate Names:
Alvespimycin hydrochloride
Application:
17-DMAG, Hydrochloride Salt is an Hsp90 inhibitor
CAS Number:
467214-21-7
Purity:
≥98%
Molecular Weight:
653.21
Molecular Formula:
C32H48N4O8•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
17-DMAG, Hydrochloride Salt is a water-soluble analog of 17-AAG (sc-200617) and geldanamycin (sc-200641). 17-DMAG, Hydrochloride Salt binds the ATP binding site of Hsp90 and inhibits its chaperone activity. It displays more potent antitumor activity than 17-AAG (mean GI50 values are 53 and 123 nM for 17-DMAG and 17-AAG respectively).
Inhibitor of:
chaperonin containing TCP1 ring complex (CCT), DnaJB3, HSP 65, HSP 90, HspBP1, HSPC016, I830012O16Rik, prefoldin 2, TID-1L, and ZNF397.Activator of:
C230078M08Rik, DnaJC7, HSP 75, HSPB11, and KCC2b.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
17-DMAG, Hydrochloride Salt, 25 mg | sc-396751 | 25 mg | $306.00 |