Molecular structure of 16α-Hydroxy Estrone, CAS Number: 566-76-7
16α-Hydroxy Estrone (CAS 566-76-7)
Application:
16α-Hydroxy Estrone is a major Estradiol metabolite
CAS Number:
566-76-7
Molecular Weight:
286.37
Molecular Formula:
C18H22O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
16α-Hydroxy Estrone is a major Estradiol metabolite. 16α-Hydroxy Estrone is an activator of Estrogen Receptor. 16α-Hydroxy estrone is a metabolite of estrone, which is a naturally occurring estrogen hormone in the body. It is formed through the hydroxylation of estrone at the 16th carbon position. This metabolite plays a role in estrogen metabolism and is involved in the regulation of estrogen-dependent processes.
16α-Hydroxy Estrone (CAS 566-76-7) References
- Evidence for interference in estradiol-17beta inactivation to estrone by oxidized low-density lipoprotein and selected lipid peroxidation products. | Abplanalp, W., et al. 1999. J Lab Clin Med. 134: 253-9. PMID: 10482310
- Estrogens and mechanisms of prostate cancer progression. | Carruba, G. 2006. Ann N Y Acad Sci. 1089: 201-17. PMID: 17261768
- In vitro short-term test evaluation of catecholestrogens genotoxicity. | Rossi, D., et al. 2007. J Steroid Biochem Mol Biol. 105: 98-105. PMID: 17590328
- Isoflavonoid-based bone-sparing treatments exert a low activity on reproductive organs and on hepatic metabolism of estradiol in ovariectomized rats. | Phrakonkham, P., et al. 2007. Toxicol Appl Pharmacol. 224: 105-15. PMID: 17655901
- Progress in solving the sex hormone paradox in pulmonary hypertension. | Lahm, T., et al. 2014. Am J Physiol Lung Cell Mol Physiol. 307: L7-26. PMID: 24816487
- Fingolimod interrupts the cross talk between estrogen metabolism and sphingolipid metabolism within prostate cancer cells. | Allam, RM., et al. 2018. Toxicol Lett. 291: 77-85. PMID: 29654831
- Identification of 16 alpha-hydroxy-estrone as a metabolite of estriol. | van Haaften, M., et al. 1988. Gynecol Endocrinol. 2: 215-21. PMID: 3227988
- The function of uterine UDP-glucuronosyltransferase 1A8 (UGT1A8) and UDP-glucuronosyltransferase 2B7 (UGT2B7) is involved in endometrial cancer based on estrogen metabolism regulation. | Zhao, F., et al. 2020. Hormones (Athens). 19: 403-412. PMID: 32592099
- The metabolism of estradiol; oral compared to intravenous administration. | Longcope, C., et al. 1985. J Steroid Biochem. 23: 1065-70. PMID: 4094413
Activator of:
Estrogen Receptor, and mPRε.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
16α-Hydroxy Estrone, 2.5 mg | sc-206281 | 2.5 mg | $220.00 | |||
16α-Hydroxy Estrone, 2.5 mg | sc-206281-CW | 2.5 mg | $275.00 |