16-(trifluoromethyl)-phenoxy Prostaglandin Lactol
Molecular Weight:
344.3
Molecular Formula:
C17H19F3O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
An F-series prostaglandin analog with potent FP agonist activity.1 Fluprostenol is used in animal reproduction as a luteolytic, while the isopropyl ester has been approved for use as an ocular hypotensive drug.2 An intermediate in the synthesis of fluprostenol. 16CF3 Lactol can be converted to the free acid of fluprostenol by Wittig reaction with commercially available reagents.
16-(trifluoromethyl)-phenoxy Prostaglandin Lactol References
1 Abramovitz, M., Adam, M., Boie, Y., et al. The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs. Biochim Biophys Acta 1483 285-293 (2000). 2 Stjernschantz, J., Resul, B. Phenyl substituted prostaglandin analogs for glaucoma treatment. Drugs of the Future 17 691-704 (1992).Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
16-(trifluoromethyl)-phenoxy Prostaglandin Lactol, 5 mg | sc-220637 | 5 mg | $235.00 | |||
16-(trifluoromethyl)-phenoxy Prostaglandin Lactol, 10 mg | sc-220637A | 10 mg | $440.00 |