Molecular structure of 16(S)-HETE, CAS Number: 183509-23-1
16(S)-HETE (CAS 183509-23-1)
Alternate Names:
16S- hydroxy- 5Z, 8Z, 11Z, 14Z- eicosatetraenoic acid
Application:
16(S)-HETE is an arachidonic acid metabolite with stereospecific biological activity
CAS Number:
183509-23-1
Molecular Weight:
320.47
Molecular Formula:
C20H32O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. 16-HETE is also shown to inhibit proximal tubule ATPase activity by as much as 60% at a concentration of 2 µM.1
16(S)-HETE (CAS 183509-23-1) References
- Arachidonic and linoleic acid derivatives impact oocyte ICSI fertilization--a prospective analysis of follicular fluid and a matched oocyte in a 'one follicle--one retrieved oocyte--one resulting embryo' investigational setting. | Ciepiela, P., et al. 2015. PLoS One. 10: e0119087. PMID: 25763593
- Significant Improvement Selected Mediators of Inflammation in Phenotypes of Women with PCOS after Reduction and Low GI Diet. | Szczuko, M., et al. 2017. Mediators Inflamm. 2017: 5489523. PMID: 28655971
- The Relationship between Eicosanoid Levels and Serum Levels of Metabolic and Hormonal Parameters Depending on the Presence of Metabolic Syndrome in Patients with Benign Prostatic Hyperplasia. | Grzesiak, K., et al. 2019. Int J Environ Res Public Health. 16: PMID: 30897712
- 5-Lipooxygenase Derivatives as Serum Biomarkers of a Successful Dietary Intervention in Patients with NonAlcoholic Fatty Liver Disease. | Banaszczak, M., et al. 2020. Medicina (Kaunas). 56: PMID: 32028646
- The Association of Free Fatty Acids and Eicosanoids with the Severity of Depressive Symptoms in Stroke Patients. | Kotlega, D., et al. 2020. Int J Mol Sci. 21: PMID: 32717948
- Lipoxins, RevD1 and 9, 13 HODE as the most important derivatives after an early incident of ischemic stroke. | Szczuko, M., et al. 2020. Sci Rep. 10: 12849. PMID: 32732956
- Fatty Acid Levels and Their Inflammatory Metabolites Are Associated with the Nondipping Status and Risk of Obstructive Sleep Apnea Syndrome in Stroke Patients. | Drozd, A., et al. 2022. Biomedicines. 10: PMID: 36140306
- Level of Potassium Is Associated with Saturated Fatty Acids in Cell Membranes and Influences the Activation of the 9 and 13 HODE and 5 HETE Synthesis Pathways in PCOS. | Szczuko, M., et al. 2022. Biomedicines. 10: PMID: 36140345
- Associations of phthalates, phthalate replacements, and their mixtures with eicosanoid biomarkers during pregnancy. | Park, S., et al. 2023. Environ Int. 178: 108101. PMID: 37487376
- Cytochrome P-450-dependent HETEs: profile of biological activity and stimulation by vasoactive peptides. | Carroll, MA., et al. 1996. Am J Physiol. 271: R863-9. PMID: 8897975
Inhibitor of:
ATPase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
16(S)-HETE, 25 µg | sc-205057 | 25 µg | $240.00 | |||
16(S)-HETE, 100 µg | sc-205057A | 100 µg | $865.00 |