Molecular structure of 15(S)- HPEPE, CAS Number: 125992-60-1
15(S)- HPEPE (CAS 125992-60-1)
Application:
15(S)- HPEPE is a primary metabolite of eicosapentaenoic acid via the 15-lipoxygenase pathway
CAS Number:
125992-60-1
Molecular Weight:
334.5
Molecular Formula:
C20H30O4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
15(S)- HPEPE is a primary metabolite of eicosapentaenoic acid via the 15-lipoxygenase pathway. Although the biological activities of 15(S)-HpEPE have not been well characterized, it is expected to behave similarly to 15(S)-HpETE (catalog number sc-200966 and sc-200966A).
15(S)- HPEPE (CAS 125992-60-1) References
- Inhibition by eicosapentaenoic acid of IL-1beta-induced PGHS-2 expression in human microvascular endothelial cells: involvement of lipoxygenase-derived metabolites and p38 MAPK pathway. | Ait-Said, F., et al. 2003. Biochim Biophys Acta. 1631: 77-84. PMID: 12573452
- 15-Hydroperoxyeicosapentaenoic acid, but not eicosapentaenoic acid, shifts arachidonic acid away from cyclooxygenase pathway into acyl-CoA synthetase pathway in rabbit kidney medulla microsomes. | Sakuma, S., et al. 2006. Prostaglandins Leukot Essent Fatty Acids. 75: 69-74. PMID: 16889947
- Structural basis for altered positional specificity of 15-lipoxygenase-1 with 5S-HETE and 7S-HDHA and the implications for the biosynthesis of resolvin E4. | Perry, SC., et al. 2022. Arch Biochem Biophys. 727: 109317. PMID: 35709965
- Lipoxygenase pathway in brown algae: The biosynthesis of novel oxylipins 'ectocarpins' by hydroperoxide bicyclase CYP5164A3 of Ectocarpus siliculosus. | Toporkova, YY., et al. 2022. Biochim Biophys Acta Mol Cell Biol Lipids. 1867: 159205. PMID: 35835431
- Lipoxene: a new group of trihydroxy pentaenes of eicosapentaenoic acid derived from porcine leukocytes. | Wong, PY., et al. 1985. Biochem Biophys Res Commun. 126: 763-72. PMID: 3838471
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
15(S)- HPEPE, 50 µg | sc-200968 | 50 µg | $74.00 |