Date published: 2026-5-19

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15(S)-15-methyl Prostaglandin F2α (CAS 35700-23-3)

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Alternate Names:
Carboprost
Application:
15(S)-15-methyl Prostaglandin F2α is an analog of PGF2α
CAS Number:
35700-23-3
Purity:
97%
Molecular Weight:
368.5
Molecular Formula:
C21H36O5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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15(S)-15-methyl Prostaglandin F2α is a chemically synthesized analog of Prostaglandin F2α, a naturally occurring prostaglandin. This analog, while mirroring the fundamental structure of its naturally occurring counterpart, Prostaglandin F2α, contains a modification: the addition of a methyl group at the 15th carbon position. This alteration imparts distinctive properties to the molecule, making it an invaluable tool in probing the intricacies of prostaglandin signaling pathways. Researchers utilize 15(S)-15-methyl Prostaglandin F2α to dissect the nuanced mechanisms through which prostaglandins interact with cellular receptors, trigger intracellular signaling cascades, and ultimately exert their effects on various biological processes. Its role extends to the exploration of the biosynthesis and metabolic pathways of prostaglandins, as well as their interactions with other lipid mediators. By employing this analog, scientists can delineate the specific actions of prostaglandins in diverse physiological and pathological contexts, such as inflammation, immune responses, and the regulation of vascular tone, without the confounding effects inherent to the more variable natural prostaglandins.


15(S)-15-methyl Prostaglandin F2α (CAS 35700-23-3) References

  1. The abortifacient effectiveness and plasma prostaglandin concentrations with 15(S)-15-methyl prostaglandin F2alpha methyl ester-containing vaginal silastic devices.  |  Lauersen, NH. and Wilson, KH. 1976. Fertil Steril. 27: 1366-73. PMID: 1001521
  2. Midtrimester abortion induced by serial intramuscular injections of 15(S)-15-methyl-prostaglandin F2alpha.  |  Lauersen, NH. and Wilson, KH. 1975. Am J Obstet Gynecol. 121: 273-6. PMID: 1115134
  3. A radioimmunoassay of 15 (S) 15 methyl prostaglandin F-2alpha.  |  Salmon, JA., et al. 1975. Prostaglandins. 9: 339-46. PMID: 1135445
  4. Serial intramuscular injections of 15(S)-15-methyl-prostaglandin F2alpha in the induction of abortion.  |  Lauersen, NH. and Wilson, KH. 1975. Prostaglandins. 10: 1029-36. PMID: 1208881
  5. Induction of midtrimester abortion by serial intravaginal administration of 15(S)-15-methyl-prostaglandin F2alpha (THAM) suppositories.  |  Lauersen, NH. and Wilson, KH. 1975. Prostaglandins. 10: 1037-45. PMID: 1208882
  6. Termination of midtrimester pregnancy by serial intramuscular injections of 15(S)-15-methyl-prostaglandin F2alpha.  |  Lauersen, NH. and Wilson, KH. 1976. Am J Obstet Gynecol. 124: 169-76. PMID: 1247053
  7. Response of the midpregnant human uterus to systemic administration of 15(S)-15-methyl-prostaglandin F2alpha.  |  Toppozada, M., et al. 1972. Prostaglandins. 2: 239-49. PMID: 4666626
  8. Intestinal absorption of prostaglandin F2alpha, 15(S)-15-methyl prostaglandin F2alpha and their methyl esters in the dog.  |  Robert, A., et al. 1974. Biochim Biophys Acta. 348: 269-78. PMID: 4847558
  9. The effects of intramuscular injections of 15(S)-15-methyl prostaglandin F2alpha in failed abortions.  |  Lauersen, NH. and Wilson, KH. 1977. Fertil Steril. 28: 1044-7. PMID: 561711
  10. Preclinical safety evaluation of 15[S]15-methyl prostaglandin F2alpha : reproduction and teratology.  |  Szczech, GM., et al. 1978. Adv Prostaglandin Thromboxane Res. 4: 157-79. PMID: 645504
  11. Pharmacotherapeutics of prostaglandin E2 and 15 (S) 15-methyl prostaglandin F2 alpha in chronic schistosomal bladder ulcer: a clinico-endoscopic study.  |  El-Gendi, MA., et al. 1982. Prostaglandins. 24: 97-104. PMID: 6956952
  12. Effect of 15(S)-15-methyl prostaglandin F2alpha on human oviductal motility and ovum transport.  |  Croxatto, HB., et al. 1978. Fertil Steril. 30: 408-14. PMID: 710612

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

15(S)-15-methyl Prostaglandin F2α, 1 mg

sc-205039
1 mg
$199.00

15(S)-15-methyl Prostaglandin F2α, 5 mg

sc-205039A
5 mg
$882.00