Date published: 2025-12-14

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15(R)-Prostaglandin F2α (CAS 37658-84-7)

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Alternate Names:
15-epi PGF2α
Application:
15(R)-Prostaglandin F2α is a less-potent epimer of the autacoid PGF2α
CAS Number:
37658-84-7
Molecular Weight:
354.5
Molecular Formula:
C20H34O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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The C-15 epimer of the naturally occurring mammalian autacoid PGF2α. It only has 25% of the potency of PGF2α in hamster antifertility studies,1 which might be due to reduced affinity for FP receptors.


15(R)-Prostaglandin F2α (CAS 37658-84-7) References

  1. Relative biological activity of certain prostaglandins and their enantiomers.  |  Miller, WL. and Sutton, MJ. 1976. Prostaglandins. 11: 77-84. PMID: 1257501
  2. Phorbol ester-induced expression of the common, low-affinity binding site for primary prostanoids in vascular smooth muscle cells.  |  Hanasaki, K., et al. 1990. J Biol Chem. 265: 4871-5. PMID: 2318870
  3. Structural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F2 alpha receptor. Implications for development of a photoaffinity probe.  |  Balapure, AK., et al. 1989. Biochem Pharmacol. 38: 2375-81. PMID: 2751699
  4. How stable is oxidative stress level? An observational study of intra- and inter-individual variability in urinary oxidative stress biomarkers of DNA, proteins, and lipids in healthy individuals.  |  Martinez-Moral, MP. and Kannan, K. 2019. Environ Int. 123: 382-389. PMID: 30572170
  5. Temporal variability in urinary pesticide concentrations in repeated-spot and first-morning-void samples and its association with oxidative stress in healthy individuals.  |  Li, AJ., et al. 2019. Environ Int. 130: 104904. PMID: 31226556
  6. Variability in urinary neonicotinoid concentrations in single-spot and first-morning void and its association with oxidative stress markers.  |  Li, AJ., et al. 2020. Environ Int. 135: 105415. PMID: 31869729
  7. Consumption of High-Oleic Soybean Oil Improves Lipid and Lipoprotein Profile in Humans Compared to a Palm Oil Blend: A Randomized Controlled Trial.  |  Baer, DJ., et al. 2021. Lipids. 56: 313-325. PMID: 33596340
  8. Hibernating brown bears are protected against atherogenic dyslipidemia.  |  Giroud, S., et al. 2021. Sci Rep. 11: 18723. PMID: 34548543
  9. Diurnal variability in urinary volatile organic compound metabolites and its association with oxidative stress biomarkers.  |  Pal, VK., et al. 2022. Sci Total Environ. 818: 151704. PMID: 34793803
  10. Effect of antioxidant-rich kindergarten meals on oxidative stress biomarkers in healthy 5-6-year-old children: a randomized controlled trial.  |  Berlic, M., et al. 2024. Eur J Pediatr. 183: 3085-3094. PMID: 38658398

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

15(R)-Prostaglandin F2α, 1 mg

sc-205036
1 mg
$90.00

15(R)-Prostaglandin F2α, 5 mg

sc-205036A
5 mg
$555.00