Date published: 2025-12-5

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15(S)-HETE Ethanolamide (CAS 161744-53-2)

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Alternate Names:
15(S)-HAEA; 15(S)-hydroxy-N-(2-hydroxyethyl)-5Z,8Z,11Z,13E-eicosatetraenamide
Application:
15(S)-HETE Ethanolamide is an agonist acting on the same receptors as THC
CAS Number:
161744-53-2
Molecular Weight:
363.5
Molecular Formula:
C22H37NO3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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15(S)-HETE Ethanolamide is a chemical compound that has been extensively investigated in scientific research, particularly within the field of lipid signaling and inflammation. It belongs to the family of endocannabinoids, which are lipid molecules that play a crucial role in modulating cellular functions. 15(S)-HETE Ethanolamide is derived from arachidonic acid and acts as an endogenous ligand for cannabinoid receptors, specifically CB1 and CB2. Through its interaction with these receptors, it influences various cellular signaling pathways involved in inflammation and immune responses. Research on 15(S)-HETE Ethanolamide has focused on its role in regulating inflammation and the immune system. Studies have investigated its impact on immune cell activation, cytokine production, and leukocyte recruitment. Furthermore, this compound has been explored in the context of neuroinflammation and neurodegenerative diseases, where it may contribute to the modulation of inflammatory processes within the central nervous system. By elucidating the mechanisms through which 15(S)-HETE Ethanolamide functions, researchers aim to deepen our understanding of lipid signaling pathways, provide insights into inflammation regulation, and contribute to the development of novel strategies for studying immune responses and inflammatory disorders.


15(S)-HETE Ethanolamide (CAS 161744-53-2) References

  1. [In a communist labor collective].  |  Denisenko, VZ. and Mikhaĭlichenko, OI. 1975. Voen Med Zh. 11-4. PMID: 1216694
  2. [The state of child health in Trujillo, Peru: survey of morbidity in children under 5 years of age].  |  Rivera Castañeda, C., et al. 1978. Bol Oficina Sanit Panam. 84: 157-71. PMID: 147091
  3. Endocannabinoid oxygenation by cyclooxygenases, lipoxygenases, and cytochromes P450: cross-talk between the eicosanoid and endocannabinoid signaling pathways.  |  Rouzer, CA. and Marnett, LJ. 2011. Chem Rev. 111: 5899-921. PMID: 21923193
  4. COX-2-derived endocannabinoid metabolites as novel inflammatory mediators.  |  Alhouayek, M. and Muccioli, GG. 2014. Trends Pharmacol Sci. 35: 284-92. PMID: 24684963
  5. Anandamide and its metabolites: what are their roles in the kidney?  |  Ritter, JK., et al. 2016. Front Biosci (Schol Ed). 8: 264-77. PMID: 27100705
  6. Changes in Retinal N-Acylethanolamines and their Oxylipin Derivatives During the Development of Visual Impairment in a Mouse Model for Glaucoma.  |  Montgomery, CL., et al. 2016. Lipids. 51: 857-66. PMID: 27221132
  7. Formation of HETE-EAs and dihydroxy derivatives in mouse kidney tissue and analysis by high-performance liquid chromatography tandem mass spectrometry.  |  Dempsey, SK., et al. 2019. J Chromatogr B Analyt Technol Biomed Life Sci. 1126-1127: 121748. PMID: 31437772
  8. Synthesis and molecular targets of N-13-hydroxy-octadienoyl-ethanolamine, a novel endogenous bioactive 15-lipoxygenase-derived metabolite of N-linoleoyl-ethanolamine found in the skin and saliva.  |  Tinto, F., et al. 2021. Biochim Biophys Acta Mol Cell Biol Lipids. 1866: 158954. PMID: 33915294
  9. Intracellular Molecular Targets and Signaling Pathways Involved in Antioxidative and Neuroprotective Effects of Cannabinoids in Neurodegenerative Conditions.  |  Tadijan, A., et al. 2022. Antioxidants (Basel). 11: PMID: 36290771
  10. Oxygenation of arachidonylethanolamide (anandamide) by lipoxygenases.  |  Ueda, N., et al. 1995. Adv Prostaglandin Thromboxane Leukot Res. 23: 163-5. PMID: 7732825
  11. Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction.  |  Felder, CC., et al. 1993. Proc Natl Acad Sci U S A. 90: 7656-60. PMID: 8395053

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

15(S)-HETE Ethanolamide, 25 µg

sc-205041
25 µg
$133.00

15(S)-HETE Ethanolamide, 50 µg

sc-205041A
50 µg
$255.00