Molecular structure of 15(R)-Prostaglandin E2, CAS Number: 38873-82-4
15(R)-Prostaglandin E2 (CAS 38873-82-4)
Alternate Names:
9-oxo-11α,15R-dihydroxy-prosta-5Z,13E-dien-1-oic acid
Application:
15(R)-Prostaglandin E2 is C-15 epimer of the naturally occurring 15(S)-PGE2 - the most physiologically abundant eicosanoid
CAS Number:
38873-82-4
Molecular Weight:
352.5
Molecular Formula:
C20H32O5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
15(R)-Prostaglandin E2 is the C-15 epimer of the naturally occurring 15(S)-PGE2 (sc-201225) isomer; the most physiologically abundant eicosanoid, which is produced predominantly from arachidonic acid (sc-200770) by COX and PGES, and exists at some level in nearly all cell types. PGE2 acts on four different receptors termed EP1 through EP4 yielding an astounding array of biological effects, but this compound shows much lower potency in most biological assays; however acid catalyzed epimerization can convert this compound to the active form - 15(S)-Prostaglandin E2.
15(R)-Prostaglandin E2 (CAS 38873-82-4) References
- Relative biological activity of certain prostaglandins and their enantiomers. | Miller, WL. and Sutton, MJ. 1976. Prostaglandins. 11: 77-84. PMID: 1257501
- Relationships between the concentrations of prostaglandins and the nonsteroidal antiinflammatory drugs indomethacin, diclofenac, and ibuprofen. | Giagoudakis, G. and Markantonis, SL. 2005. Pharmacotherapy. 25: 18-25. PMID: 15767216
- Cardiovascular actions of prostaglandins D and E in the sheep: evidence for two distinct receptors. | Jones, RL. 1976. Adv Prostaglandin Thromboxane Res. 1: 221-30. PMID: 187037
- Stability of prostaglandin E1 and dinoprostone (prostaglandin E2) under strongly acidic and basic conditions. | Stehle, RG. and Oesterling, TO. 1977. J Pharm Sci. 66: 1590-5. PMID: 21282
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
15(R)-Prostaglandin E2, 1 mg | sc-205035 | 1 mg | $60.00 | |||
15(R)-Prostaglandin E2, 5 mg | sc-205035A | 5 mg | $272.00 |