Molecular structure of 15(R)-Prostaglandin E1, CAS Number: 20897-91-0
15(R)-Prostaglandin E1 (CAS 20897-91-0)
Application:
15(R)-Prostaglandin E1 is the C-15 stereoisomer of PGE1 and an inhibitor of 15-hydroxy PGDH
CAS Number:
20897-91-0
Molecular Weight:
354.5
Molecular Formula:
C20H34O5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
15(R)-PGE1 is the "unnatural" C-15 stereoisomer of PGE1. It is basically inactive biologically when compared to PGE1.1 It is a non-competitive inhibitor of 15-hydroxy PGDH with an IC50 of 189 µM.2
15(R)-Prostaglandin E,[object Object], (CAS 20897-91-0) References
1 Nakano, J. Relationship between the chemical structure of prostaglandins and their vasoactivities in dogs. Br J Pharmacol 44 63-70 (1972). 2 Jarabak, J., Braithwaite, S.S. Kinetic studies on a 15-hydroxyprostaglandin dehydrogenase from human placenta. The reaction mechanism and the mechanism of action of various inhibitors. Arch Biochem Biophys 177 245-254 (1976).Inhibitor of:
PGDH.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
15(R)-Prostaglandin E1, 1 mg | sc-205034 | 1 mg | $76.00 | |||
15(R)-Prostaglandin E1, 5 mg | sc-205034A | 5 mg | $259.00 |