Molecular structure of 15(R),19(R)-hydroxy Prostaglandin E2, CAS Number: 54142-29-9
15(R),19(R)-hydroxy Prostaglandin E2 (CAS 54142-29-9)
Alternate Names:
15(R),19(R)-hydroxy PGE2
Application:
15(R),19(R)-hydroxy Prostaglandin E2 is acts as an agonist of EP2 receptors - used for deconvoluting EP-receptor function
CAS Number:
54142-29-9
Molecular Weight:
368.5
Molecular Formula:
C20H32O6
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
15(R),19(R)-hydroxy Prostaglandin E2 is the inverse or "unnatural" isomer at C-15 of 19(R)-Hydroxy-prostaglandin E2 (sc-201252). These 19-hydroxylated prostaglandins have been associated with selectively agonizing EP2 receptors, contrary to PGE2 (sc-201225), which can activate a variety of prostanoid receptor types. The ability of these 19-hydroxylated prostaglandins to selectively agonize EP2 receptors is useful in the deconvolution of EP-receptor function.
15(R),19(R)-hydroxy Prostaglandin E2 (CAS 54142-29-9) References
- Prostanoids stimulate K secretion and Cl secretion in guinea pig distal colon via distinct pathways. | Halm, DR. and Halm, ST. 2001. Am J Physiol Gastrointest Liver Physiol. 281: G984-96. PMID: 11557519
- The measurement of E and 19-hydroxy E prostaglandins in human seminal plasma. | Cooper, I. and Kelly, RW. 1975. Prostaglandins. 10: 507-14. PMID: 1197784
- Lack of interaction between prostaglandin E2 receptor subtypes in regulating adenylyl cyclase activity in cultured rat dorsal root ganglion cells. | Wise, H. 2006. Eur J Pharmacol. 535: 69-77. PMID: 16545798
- Identification of 19 (R)-OH prostaglandin E2 as a selective prostanoid EP2-receptor agonist. | Woodward, DF., et al. 1993. Prostaglandins. 46: 371-83. PMID: 8248550
Activator of:
EP2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
15(R),19(R)-hydroxy Prostaglandin E2, 50 µg | sc-205037 | 50 µg | $62.00 | |||
15(R),19(R)-hydroxy Prostaglandin E2, 100 µg | sc-205037A | 100 µg | $118.00 |