Molecular structure of 15-keto Prostaglandin E1, CAS Number: 22973-19-9
15-keto Prostaglandin E1 (CAS 22973-19-9)
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Alternate Names:
9,15-dioxo-11α-hydroxy-prost-13E-en-1-oic acid
Application:
15-keto Prostaglandin E1 is the inactive metabolite of PGE1 produced by 15-hydroxy PGDH
CAS Number:
22973-19-9
Molecular Weight:
352.5
Molecular Formula:
C20H32O5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
15-keto Prostaglandin E1 is the inactive metabolite of PGE1 produced by 15-hydroxy PGDH. It has greatly reduced biological activity compared to PGE1. 15-keto Prostaglandin E1 is a naturally occurring compound that acts as an endogenous agonist of the peroxisome proliferator-activated receptor. It is an important regulator of various physiological processes within the body.
15-keto Prostaglandin E1 (CAS 22973-19-9) References
- Synergism between PGE1-metabolites(13,14-dihydro-prostaglandin E1, 15-keto prostaglandin E1, 15-keto-13,14-dihydro-prostaglandin E1) and nitric oxide (NO) on platelet aggregation. | Katzenschlager, R., et al. 1992. Prostaglandins Leukot Essent Fatty Acids. 45: 207-10. PMID: 1589447
- Jet nebulization of prostaglandin E1 during neonatal mechanical ventilation: stability, emitted dose and aerosol particle size. | Sood, BG., et al. 2007. Pharmacol Res. 56: 531-41. PMID: 17997106
- Molecular characterization of lung dysplasia induced by c-Raf-1. | Rohrbeck, A., et al. 2009. PLoS One. 4: e5637. PMID: 19529782
- Purification and characterization of a 15-ketoprostaglandin delta 13-reductase from bovine lung. | Hansen, HS. 1979. Biochim Biophys Acta. 574: 136-45. PMID: 224937
- Transcriptomic and Metabolomic Analysis of the Effects of Exogenous Trehalose on Salt Tolerance in Watermelon (Citrullus lanatus). | Yuan, G., et al. 2022. Cells. 11: PMID: 35954182
- Pathways of prostaglandin F2alpha metabolism in mammalian kidneys. | Hoult, JR. and Moore, PK. 1977. Br J Pharmacol. 61: 615-26. PMID: 597667
- 15-Hdroxyprostaglandin dehydrogenase activity in vitro in lung and kidney of essential fatty acid-deficient rats. | Hansen, HS. and Toft, BS. 1978. Biochim Biophys Acta. 529: 230-6. PMID: 656454
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
15-keto Prostaglandin E1, 500 µg | sc-205024 | 500 µg | $62.00 | |||
15-keto Prostaglandin E1, 1 mg | sc-205024A | 1 mg | $118.00 |