Molecular structure of 15-keto Latanoprost (free acid)
15-keto Latanoprost (free acid)
Molecular Weight:
388.5
Molecular Formula:
C23H32O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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A potential metabolite of Latanoprost when administered to intact animals. Also one of the common minor impurities found in commercial preparations of the bulk drug compound. Although much less potent than the parent compound Latanoprost, 15-keto Latanoprost still retains the ability to produce a small but measurable decrease (1 mm Hg) in the intraocular pressure of normal cynomolgus monkeys when administered at a dose of 1 µg/eye.1 15-keto Latanoprost is also a miotic in the normal cat eye, causing an 8 mm Hg reduction in pupillary diameter at 5 µg/eye. Again, this is not as potent as many other F-type prostaglandins.
15-keto Latanoprost (free acid) References
1 Stjernschantz, J., Resul, B. Phenyl substituted prostaglandin analogs for glaucoma treatment. Drugs of the Future 17 691-704 (1992).Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
15-keto Latanoprost (free acid), 1 mg | sc-220623 | 1 mg | $60.00 | |||
15-keto Latanoprost (free acid), 5 mg | sc-220623A | 5 mg | $270.00 |