Molecular structure of 15-Acetoxyscirpenol, CAS Number: 2623-22-5
15-Acetoxyscirpenol (CAS 2623-22-5)
Alternate Names:
15-Acetoxyscirpen-3,4-diol
Application:
15-Acetoxyscirpenol is a trichothecene mycotoxin and an apoptosis inducer
CAS Number:
2623-22-5
Molecular Weight:
324.37
Molecular Formula:
C17H24O6
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
15-Acetoxy Scirpenol, a trichothecene mycotoxin exhibits the ability to induce apoptotic cell death in human Jurkat T cells. It is also known as 15-Acetoxyscirpenol, which is classified as a trichothecene mycotoxin and an apoptosis inducer. Furthermore, another trichothecene mycotoxin called Monoacetoxyscirpenol, also referred to as 4-deacetylanguidin or 15-acetylscirpenetriol, falls within the category of organic compounds known as trichothecenes. These compounds are characterized by the presence of an epoxide ring and a benzopyran derivative, which may have varying numbers of hydroxyl, acetyl, or other substituents.
15-Acetoxyscirpenol (CAS 2623-22-5) References
- Fast methods for screening of trichothecenes in fungal cultures using gas chromatography-tandem mass spectrometry. | Nielsen, KF. and Thrane, U. 2001. J Chromatogr A. 929: 75-87. PMID: 11594405
- Simultaneous quantification of A-trichothecene mycotoxins in grains using liquid chromatography-atmospheric pressure chemical ionisation mass spectrometry. | Razzazi-Fazeli, E., et al. 2002. J Chromatogr A. 968: 129-42. PMID: 12236496
- The use of tissue culture for the detection of mycotoxins. | Robb, J., et al. 1990. Lett Appl Microbiol. 10: 161-5. PMID: 1366585
- Induction of apoptosis by disturbing mitochondrial-membrane potential and cleaving PARP in Jurkat T cells through treatment with acetoxyscirpenol mycotoxins. | Lee, DH., et al. 2006. Biol Pharm Bull. 29: 648-54. PMID: 16595895
- Inhibition of sodium glucose cotransporter-I expressed in Xenopus laevis oocytes by 4-acetoxyscirpendiol from Cordyceps takaomantana (anamorph = Paecilomyces tenuipes). | Yoo, O. and Lee, DH. 2006. Med Mycol. 44: 79-85. PMID: 16805097
- First Report on the Occurrence of Fusarium langsethiae Isolated from Wheat Kernels in Poland. | Lukanowski, A., et al. 2008. Plant Dis. 92: 488. PMID: 30769700
- Development of a sensitive enzyme-linked immunosorbent assay for the detection of diacetoxyscirpenol. | Klaffer, U., et al. 1988. Int J Food Microbiol. 6: 9-17. PMID: 3079464
- Fusarium Species Pathogenic to Barley and Their Associated Mycotoxins. | Salas, B., et al. 1999. Plant Dis. 83: 667-674. PMID: 30845619
- Production and characterization of a monoclonal antibody to the trichothecene mycotoxin diacetoxyscirpenol. | Pauly, JU., et al. 1988. Biol Chem Hoppe Seyler. 369: 487-92. PMID: 3202955
- Combination of Extrusion and Fermentation with Lactobacillus plantarum and L. uvarum Strains for Improving the Safety Characteristics of Wheat Bran. | Bartkiene, E., et al. 2021. Toxins (Basel). 13: PMID: 33669853
- Trichothecene structure and toxicity to the green alga Chlorella pyrenoidosa. | Ikawa, M., et al. 1985. Toxicon. 23: 535-7. PMID: 4024150
- Production of 3-acetoxyscirpene-4,15-diol from anguidine (4,15-diacetoxyscirpene-3-ol) by Fusarium oxysporum f.sp. vasinfectum. | Claridge, CA. and Schmitz, H. 1979. Appl Environ Microbiol. 37: 693-6. PMID: 453837
- Structure-activity relationships and interactions among trichothecene mycotoxins as assessed by yeast bioassay. | Madhyastha, MS., et al. 1994. Toxicon. 32: 1147-52. PMID: 7801350
- Molecular phylogenetic, morphological, and mycotoxin data support reidentification of the Quorn mycoprotein fungus as Fusarium venenatum. | O'Donnell, K., et al. 1998. Fungal Genet Biol. 23: 57-67. PMID: 9501477
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
15-Acetoxyscirpenol, 1 mg | sc-391528 | 1 mg | $175.00 |