13(S)-HOTrE(γ) (CAS 74784-20-6)

13(S)-HOTrE(γ), with the CAS number 74784-20-6, is a specific enantiomer of hydroxyoctadecatrienoic acid, distinguished by its S-configuration and the gamma (γ) designation. This compound is a hydroxylated form of linolenic acid, a process typically mediated by lipoxygenases, a class of enzymes that introduce molecular oxygen into polyunsaturated fatty acids. As a research chemical, 13(S)-HOTrE(γ) is extensively used to study the biochemical pathways involved in lipid metabolism and the regulatory mechanisms of fatty acids in cellular processes. The specific actions of this molecule include the modulation of signaling pathways that regulate inflammation, cell proliferation, and apoptosis. It operates primarily through its interaction with various cellular receptors, such as peroxisome proliferator-activated receptors (PPARs), which play a critical role in lipid signaling and metabolism. This interaction often results in changes to gene expression patterns that influence cellular behavior. In biochemical and cellular biology research, 13(S)-HOTrE(γ) is instrumental in elucidating the roles of hydroxylated fatty acids in maintaining cellular homeostasis and responding to physiological stresses. By studying this molecule, researchers gain insights into the complex dynamics of lipid signaling in health and the response mechanisms to oxidative stress, providing a deeper understanding of the pathways that govern cell function and adaptation.