13(S)-HpOTrE (CAS 67597-26-6)

13(S)-HpOTrE, with the CAS number 67597-26-6, is a hydroperoxy derivative of octadecatrienoic acid, characterized specifically as the S-enantiomer. This biochemical is synthesized through the action of lipoxygenase enzymes on linolenic acid, resulting in the introduction of a hydroperoxy group. As a member of the hydroperoxy fatty acids, 13(S)-HpOTrE is heavily utilized in biochemical research to study the complex pathways of lipid peroxidation and its subsequent roles in cellular signaling. This compound is particularly important for its participation in the initial steps of the biosynthesis of various bioactive lipid mediators. These mediators are crucial for modulating diverse cellular functions, such as immune responses and the regulation of inflammatory processes. In research settings, 13(S)-HpOTrE serves as a vital tool for exploring how cells utilize oxidized lipids to communicate and respond to environmental stimuli. Studies involving this compound help explain the formation and action of downstream metabolites, including different types of leukotrienes and resolvins, which play key roles in resolving inflammation and promoting tissue healing. By understanding the behavior and impact of 13(S)-HpOTrE in cellular environments, researchers can gain deeper insights into lipid signaling pathways and their effects on cellular health and adaptation.