Date published: 2025-12-19

1-800-457-3801

SCBT Portrait Logo
Seach Input

13-cis Retinoic Acid-d5

5.0(1)
Write a reviewAsk a question

Alternate Names:
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2Z,4E,6E,8E-nonatetranenoic Acid-d5; Isotretinoin-d5; 13-cis-Vitamin A Acid-d5; Accutane-d5; Isotretinoin-d5; Isotrex-d5; IsotrexGel-d5; Neovitamin A Acid-d5; Ro 4-3780-d5; Roaccutan-d5; Roaccutane-d5
Application:
13-cis Retinoic Acid-d5 is a labeled retinoid and teratagen used for severe acne treatment
Molecular Weight:
305.47
Molecular Formula:
C20H23D5O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

13-cis Retinoic Acid-d5 is a stable isotope of 13-cis Retinoic Acid, a biologically active metabolite of vitamin A. It functions as a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR) nuclear receptors. Upon binding to these receptors, 13-cis Retinoic Acid-d5 modulates gene expression, leading to the regulation of cellular differentiation, proliferation, and apoptosis. Its mechanism of action involves the activation of specific DNA sequences, known as retinoic acid response elements (RAREs), which are present in the regulatory regions of target genes. This activation ultimately leads to the modulation of various cellular processes, including the regulation of cell growth and development. 13-cis Retinoic Acid-d5 may play a role in the regulation of immune function and inflammation through its interaction with nuclear receptors. 13-cis Retinoic Acid-d5 is used for studying the molecular mechanisms underlying the biological effects of retinoic acid in cellular and developmental processes.


13-cis Retinoic Acid-d5 References

  1. Selective brain penetrable Nurr1 transactivator for treating Parkinson's disease.  |  Wang, J., et al. 2016. Oncotarget. 7: 7469-79. PMID: 26862735
  2. Isotretinoin administration improves sperm production in men with infertility from oligoasthenozoospermia: a pilot study.  |  Amory, JK., et al. 2017. Andrology. 5: 1115-1123. PMID: 28980413
  3. Commensals Suppress Intestinal Epithelial Cell Retinoic Acid Synthesis to Regulate Interleukin-22 Activity and Prevent Microbial Dysbiosis.  |  Grizotte-Lake, M., et al. 2018. Immunity. 49: 1103-1115.e6. PMID: 30566883

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

13-cis Retinoic Acid-d5, 1 mg

sc-213606
1 mg
$550.00