Date published: 2025-10-6

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13,14-dihydro Prostaglandin F1α (CAS 20592-20-5)

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Alternate Names:
9α,11α,15S-trihydroxy-prostan-1-oic acid
Application:
13,14-dihydro Prostaglandin F1α is a potential metabolite of PGF1α
CAS Number:
20592-20-5
Molecular Weight:
358.51
Molecular Formula:
C20H38O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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13,14-dihydro Prostaglandin F1α is a compound that functions as a potent vasodilator, playing a role in the regulation of blood flow and vascular tone. It acts by binding to specific prostaglandin receptors on smooth muscle cells, leading to the activation of adenylate cyclase and subsequent increase in intracellular levels of cyclic adenosine monophosphate (cAMP). This increase in cAMP levels then triggers a cascade of intracellular events that ultimately result in relaxation of the smooth muscle, leading to vasodilation. 13,14-dihydro Prostaglandin F1α may inhibit platelet aggregation, further contributing to its role in regulating vascular function. At the molecular level, 13,14-dihydro Prostaglandin F1α exerts its effects by modulating the activity of various enzymes and ion channels involved in smooth muscle contraction and platelet aggregation, ultimately leading to its vasodilatory and anti-aggregatory effects.


13,14-dihydro Prostaglandin F1α (CAS 20592-20-5) References

  1. The synthesis and human FP receptor binding affinity of 13,14-dihydro prostaglandin F1alpha sulfonamides: potential treatments for osteoporosis.  |  Wang, Y., et al. 2000. Chem Pharm Bull (Tokyo). 48: 1332-7. PMID: 10993232
  2. Measurement of initial prostaglandin F metabolites in medium of BALB/c 3T3 and SV3T3 mouse fibroblasts cultures.  |  Ritzi, EM., et al. 1975. Biochem Biophys Res Commun. 63: 179-86. PMID: 1168462
  3. The biological activities of three metabolites of prostaglandin E 1.  |  Anggård, E. 1966. Acta Physiol Scand. 66: 509-10. PMID: 5951401

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

13,14-dihydro Prostaglandin F1α, 1 mg

sc-204995
1 mg
$60.00

13,14-dihydro Prostaglandin F1α, 5 mg

sc-204995A
5 mg
$272.00