Molecular structure of 13,14-dihydro Prostaglandin E1-d4
13,14-dihydro Prostaglandin E1-d4
Alternate Names:
Prostaglandin E0-D4; 13,14-dh PGE1-d4
Molecular Weight:
360.5
Molecular Formula:
C20H32D4O5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Contains four deuterium atoms at the 3, 3′, 4, and 4′ positions. intended for use as an internal standard for the quantification of 13,14-dh PGE1 by GC- or LC-mass spectrometry. An inhibitor of ADP-induced platelet aggregation in human platelet-rich plasma and washed platelets with IC50 values of 31 and 21 nM, respectively.1 13,14-dh PGE1 is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE1 which has an IC50 of 40 nM.2 Also, 13,14-dh PGE1 activates adenylate cyclase in NCB-20 hybrid cells with a Kact of 668 nM.3
13,14-dihydro Prostaglandin E1-d4 References
- Prostacyclin-dependent activation of adenylate cyclase in a neuronal somatic cell hybrid: prostanoid structure-activity relationships. | Blair, IA., et al. 1980. Br J Pharmacol. 69: 519-25. PMID: 6249437
- Comparison of the inhibitory effect of E-prostaglandins in human and rabbit platelet-rich plasma and washed platelets. | Kobzar, G., et al. 1993. Comp Biochem Physiol C Comp Pharmacol Toxicol. 106: 489-94. PMID: 7904921
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
13,14-dihydro Prostaglandin E1-d4, 25 µg | sc-220593 | 25 µg | $99.00 | |||
13,14-dihydro Prostaglandin E1-d4, 50 µg | sc-220593A | 50 µg | $188.00 |