13,14-dihydro-15-keto Prostaglandin J2
Molecular Weight:
334.5
Molecular Formula:
C20H30O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Various biological properties exist for both PGJ2 and its metabolites such as inhibition of platelet aggregation, antitumor, and antiviral activity.1,2 It is the dehydration product of 13,14-dihydro-15-keto PGD2 and is a presumed metabolite of PGJ2 via the 15-hydroxy PG dehydrogenase pathway. There are no published studies of the pharmacological properties or the formation of 13,14-dihydro-15-keto PGJ2.
13,14-dihydro-15-keto Prostaglandin J2 References
- Antitumor activity, optimum administration method and pharmacokinetics of 13,14-dihydro-15-deoxy-deoxy-Delta7 -prostaglandin A1 methyl ester (TEI-9826) integrated in lipid microspheres (Lipo TEI-9826). | Fukushima, S., et al. 2001. Anticancer Drugs. 12: 221-34. PMID: 11290870
- Methanol Extract of Coleus amboinicus (Lour) Exhibited Antiproliferative Activity and Induced Programmed Cell Death in Colon Cancer Cell WiDr. | Laila, F., et al. 2020. Int J Food Sci. 2020: 9068326. PMID: 32047805
- Integrated analysis of effect of daisaikoto, a traditional Japanese medicine, on the metabolome and gut microbiome in a mouse model of nonalcoholic fatty liver disease. | Ishizawa, S., et al. 2022. Gene. 846: 146856. PMID: 36067864
- Analysis of the pharmacodynamic difference between Xiaojin Pills taken with Chinese Baijiu and water based on serum pharmacochemistry and pharmacokinetics. | Song, J., et al. 2023. J Ethnopharmacol. 300: 115723. PMID: 36115600
- Associations of phthalates, phthalate replacements, and their mixtures with eicosanoid biomarkers during pregnancy. | Park, S., et al. 2023. Environ Int. 178: 108101. PMID: 37487376
- Colonic microflora and plasma metabolite-based comparative analysis of unilateral ureteral obstruction-induced chronic kidney disease after treatment with the Chinese medicine FuZhengHuaYuJiangZhuTongLuo and AST-120. | Chen, Z., et al. 2024. Heliyon. 10: e24987. PMID: 38333870
- Associations of maternal blood metal concentrations with plasma eicosanoids among pregnant women in Puerto Rico. | Kim, C., et al. 2024. Sci Total Environ. 928: 172295. PMID: 38588744
- Synthesis and platelet aggregation inhibiting activity of prostaglandin D analogues. | Bundy, GL., et al. 1983. J Med Chem. 26: 790-9. PMID: 6854581
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
13,14-dihydro-15-keto Prostaglandin J2, 500 µg | sc-220599 | 500 µg | $112.00 | |||
13,14-dihydro-15-keto Prostaglandin J2, 1 mg | sc-220599A | 1 mg | $214.00 |